A zinc fluorescent sensor used to detect mercury (II) and hydrosulfide

Publication date: 5 May 2017
Source:Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, Volume 178
Author(s): Jae Min Jung, Jae Jun Lee, Eunju Nam, Mi Hee Lim, Cheal Kim, Roger G. Harrison
A zinc sensor based on quinoline and morpholine has been synthesized. The sensor selectively fluoresces in the presence of Zn²⁺, while not for other metal ions. Absorbance changes in the 350nm region are observed when Zn²⁺ binds, which binds in a 1:1 ratio. The sensor fluoresces due to Zn²⁺ above pH values of 6.0 and in the biological important region. The Zn²⁺-sensor complex has the unique ability to detect both Hg²⁺ and HS⁻. The fluorescence of the Zn²⁺-sensor complex is quenched when it is exposed to aqueous solutions of Hg²⁺ with sub-micromolar detection levels for Hg²⁺. The fluorescence of the Zn²⁺-sensor complex is also quenched by aqueous solutions of hydrosulfide. The sensor was used to detect Zn²⁺ and Hg²⁺ in living cells.

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