Coxsackievirus and Type 1 Diabetes Mellitus: The Wolf’s Footprints

Publication date: Available online 8 January 2018
Source:Trends in Endocrinology & Metabolism
Author(s): Decio L. Eizirik, Anne Op de Beeck
Enteroviruses are important environmental contributors to islet inflammation (insulitis) in type 1 diabetes mellitus (T1DM). A recent study characterized the proteomic alterations induced by Coxsackievirus type B (CVB) infection of human islets. This provides relevant information to decipher the words of the virus-induced 'dialog' between β cells and the immune system that leads to autoimmunity.



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