A Developmental Switch in Microglial HDAC Function

Publication date: 20 March 2018
Source:Immunity, Volume 48, Issue 3
Author(s): Hansruedi Mathys, Jay Penney, Li-Huei Tsai
The epigenetic mechanisms controlling microglia functions are largely unknown. In this issue of Immunity, Datta et al. (2018) uncover surprising and distinct effects of deleting the epigenetic regulators HDAC1 and HDAC2 during microglial development versus during the course of neurodegeneration.

Teaser

The epigenetic mechanisms controlling microglia functions are largely unknown. In this issue of Immunity, Datta et al. (2018) uncover surprising and distinct effects of deleting the epigenetic regulators HDAC1 and HDAC2 during microglial development versus during the course of neurodegeneration.


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