A Talented Duo: IFIT1 and IFIT3 Patrol Viral RNA Caps

Publication date: 20 March 2018
Source:Immunity, Volume 48, Issue 3
Author(s): Youn Jung Choi, James W. Bowman, Jae U. Jung
Hosts respond to viral infection by expressing interferon-stimulated genes, of which IFITs are potent inhibitors of viral RNA translation. Johnson et al. (2018) solved the structure of the IFIT1-IFIT3 complex bound cap 0 RNA and explored their concerted antiviral activity.

Teaser

Hosts respond to viral infection by expressing interferon-stimulated genes, of which IFITs are potent inhibitors of viral RNA translation. Johnson et al. (2018) solved the structure of the IFIT1-IFIT3 complex bound cap 0 RNA and explored their concerted antiviral activity.


http://ift.tt/2FOcwR8