Engineering Control over 3D Morphogenesis by Tissue Origami

Publication date: 22 January 2018
Source:Developmental Cell, Volume 44, Issue 2
Author(s): Mahmut Selman Sakar, Brendon M. Baker
Controlled folding of tissues occurs in development and would enable advances in tissue engineering. In this issue of Developmental Cell, Hughes et al. (2018) use in vivo, in vitro, and in silico approaches to uncover blueprints of microscale mesenchymal cell distribution that robustly drives macroscopic 3D folding of tissues.

Teaser

Controlled folding of tissues occurs in development and would enable advances in tissue engineering. In this issue of Developmental Cell, Hughes et al. (2018) use in vivo, in vitro, and in silico approaches to uncover blueprints of microscale mesenchymal cell distribution that robustly drives macroscopic 3D folding of tissues.


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