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Παρασκευή 11 Ιανουαρίου 2019

Dark skin phototype is associated with more severe ocular complications of Stevens‐Johnson syndrome and toxic epidermal necrolysis

Abstract

Stevens‐Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are acute severe skin reactions with extensive apoptosis of the epidermis and mucous membranes. Ocular involvement occurs in up to 75% of patients at the acute phase, described as mild, moderate and severe involvement and may result in long‐term severe sequelae with dryness, photophobia, cicatrising conjunctivitis complicated with corneal vascularisation and scarring, which may result in severe visual loss. The acute management of SJS/TEN ocular complications has not been codified.

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