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Παρασκευή 11 Ιανουαρίου 2019

MULTIPLE FACIAL PLAQUE VARIANT OF TRICHOBLASTOMA

Background

The plaque variant of trichoblastoma has been described as a solitary tumor with diffuse infiltration in the lower dermis and hypodermis with poorly defined borders. Herein, we report a new variant of multiple centrofacial trichoblastoma.

Object

To describe clinical and pathological features of a new multiple kind of plaque variant of centrofacial trichoblastoma.

Methods

Case series of patients with a multiple plaque variant of centrofacial trichoblastoma treated in our department between 2005 and 2017. We identified 8 patients with the centrofacial plaque variant of trichoblastoma treated in our department from 2005 to 2017.

Results

The final study sample comprised 13 trichoblastomas from four patients. All patients also developed at least one basal cell carcinoma. Mohs surgery was the method of treatment in the majority of the cases of trichoblastoma and in all the cases of basal cell carcinoma. We needed between 2 and 6 stages to obtain free margins in our cases of facial plaque trichoblastomas treated by Mohs surgery.

Conclusion

To the best of our knowledge, a multiple plaque variant of trichoblastoma has not been described in the literature. We suggest a genetic origin of this variant of trichoblastoma and describe its remarkable infiltrative nature, with poorly defined surgical margins.

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