Spineless Behavior of CX3CR1+ Monocytes in Response to Infection

Publication date: 18 July 2017
Source:Immunity, Volume 47, Issue 1
Author(s): Paul A. Muller, Daniel Mucida
Sickness in mammals can lead to cognition deficits, although the underlying mechanisms remain elusive. In a recent Nature Medicine article, Garré et al. (2017) report that sickness-induced cortical dendritic spine loss and impaired memory formation is mediated by CX3CR1⁺ monocyte-derived TNF-α.

Teaser

Sickness in mammals can lead to cognition deficits, although the underlying mechanisms remain elusive. In a recent Nature Medicine article, Garré et al. (2017) report that sickness-induced cortical dendritic spine loss and impaired memory formation is mediated by CX3CR1⁺ monocyte-derived TNF-α.


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