Cosmetics, Vol. 4, Pages 54: Cosmetic Potential of a Liotropic Liquid Crystal Emulsion Containing Resveratrol

Cosmetics, Vol. 4, Pages 54: Cosmetic Potential of a Liotropic Liquid Crystal Emulsion Containing Resveratrol

Cosmetics doi: 10.3390/cosmetics4040054

Authors: Laura Bonato Alves Oliveira Rafaela Oliveira Camila Oliveira Nádia Raposo Marcos Brandão Anderson Ferreira Hudson Polonini

Resveratrol is a natural substance that has been the target of many researchers over the years since it presents a variety of potential applications in the areas of cosmetics and medicine as a treatment for some diseases. Due to its high antioxidant capacity but low bioavailability, we evaluated the antiaging potential of resveratrol as a liotropic liquid crystal emulsion. Initially, we performed in vitro assays to quantify both the organoleptic characteristics and stability of the emulsion. Next, an in vivo trial was performed on the faces of 30 volunteers to determine the cream's cosmetic potential and to measure porphyrins, skin barrier function, skin pigmentation, expression lines, and porosity. The emulsion maintained its characteristics during the in vitro assays and, in the in vivo trial, it had some effect only on pore size in forehead, without any significant effects on the other parameters. We had 6 dropouts throughout the study, then the final number of volunteers was 24. Most volunteers did not show any changes in skin pigmentation throughout the study. Similarly, there was not any noticeable improvement on any other parameters evaluated. However, volunteers related a high level of satisfaction with the product.

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