Related ArticlesTetrahedral DNA Nanostructure-Delivered DNAzyme for Gene Silencing to Suppress Cell Growth. ACS Appl Mater Interfaces. 2019 Feb 20;11(7):6850-6857 Authors: Meng L, Ma W, Lin S, Shi S, Li Y, Lin Y Abstract DNAzymes are synthetic oligonucleotides that are capable of cleavaging target mRNA to exert gene-silencing activity and are considered as promising therapeutic agents. Dz13 is a DNAzyme that cleaves the mRNA of c-Jun and suppresses...
Sun Jun 30, 2019 13:53
Related ArticlesRemote Induction of Cell Autophagy by 2D MoS2 Nanosheets via Perturbing Cell Surface Receptors and mTOR Pathway from Outside of Cells. ACS Appl Mater Interfaces. 2019 Feb 20;11(7):6829-6839 Authors: Zhou X, Jia J, Luo Z, Su G, Yue T, Yan B Abstract The ability of nanoparticles to induce adverse consequences in human cells relies on their physical shapes. In this aspect, how two-dimensional nanoparticles differ from three-dimensional...
Sun Jun 30, 2019 13:53
Related ArticlesMechanical Strength, Biodegradation, and in Vitro and in Vivo Biocompatibility of Zn Biomaterials. ACS Appl Mater Interfaces. 2019 Feb 20;11(7):6809-6819 Authors: Zhu D, Cockerill I, Su Y, Zhang Z, Fu J, Lee KW, Ma J, Okpokwasili C, Tang L, Zheng Y, Qin YX, Wang Y Abstract Zn-based biomaterials have emerged as promising new types of bioresorbable metallics applicable to orthopedic devices, cardiovascular stents, and other medical applications...
Sun Jun 30, 2019 13:53
Related ArticlesBiomimicry Recognition of Proteins and Cells Using a Small Array of Block Copolymers Appended with Amino Acids and Fluorophores. ACS Appl Mater Interfaces. 2019 Feb 20;11(7):6751-6758 Authors: Tomita S, Ishihara S, Kurita R Abstract Mimicking sensory principles encountered in animals, whereby numerous tastants and odorants are identified based on "pattern"-like sensory inputs that are generated by arrays of sensory cells, allows creating...
Sun Jun 30, 2019 13:53
Related ArticlesRecent Advances in Flexible and Wearable Pressure Sensors Based on Piezoresistive 3D Monolithic Conductive Sponges. ACS Appl Mater Interfaces. 2019 Feb 20;11(7):6685-6704 Authors: Ding Y, Xu T, Onyilagha O, Fong H, Zhu Z Abstract High-performance flexible strain and pressure sensors are important components of the systems for human motion detection, human-machine interaction, soft robotics, electronic skin, etc., which are envisioned...
Sun Jun 30, 2019 13:53
Related ArticlesMnCO3 as a New Electrochemiluminescence Emitter for Ultrasensitive Bioanalysis of β-Amyloid1-42 Oligomers Based on Site-Directed Immobilization of Antibody. ACS Appl Mater Interfaces. 2019 Feb 20;11(7):7157-7163 Authors: Jia Y, Yang L, Feng R, Ma H, Fan D, Yan T, Feng R, Du B, Wei Q Abstract In this work, an electrochemiluminescence (ECL) immunosensor utilizing MnCO3 nanospheres as a novel ECL luminophor and the HWRGWVC (HC-7) heptapeptide...
Sun Jun 30, 2019 13:53
Related ArticlesEngineering of Bone- and CD44-Dual-Targeting Redox-Sensitive Liposomes for the Treatment of Orthotopic Osteosarcoma. ACS Appl Mater Interfaces. 2019 Feb 20;11(7):7357-7368 Authors: Feng S, Wu ZX, Zhao Z, Liu J, Sun K, Guo C, Wang H, Wu Z Abstract This study aimed to develop an efficient step-by-step osteosarcoma (OS)-targeting liposome system functionalized with a redox-cleavable, bone- and cluster of differentiation 44 (CD44)-dual-targeting...
Sun Jun 30, 2019 13:53
Related ArticlesInterlocked Graphene Oxide Provides Narrow Channels for Effective Water Desalination through Forward Osmosis. ACS Appl Mater Interfaces. 2019 Feb 20;11(7):7566-7575 Authors: Padmavathy N, Behera SS, Pathan S, Das Ghosh L, Bose S Abstract Unique two-dimensional water channels formed by stacked graphene oxide (GO) sheets that are "nonleachable" and nonswellable can show great potential for water remediation. The interlayer spacing controls...
Sun Jun 30, 2019 13:53
Related ArticlesBiocompatible Heat-Shock Protein Inhibitor-Delivered Flowerlike Short-Wave Infrared Nanoprobe for Mild Temperature-Driven Highly Efficient Tumor Ablation. ACS Appl Mater Interfaces. 2019 Feb 20;11(7):6820-6828 Authors: Jiang A, Liu Y, Ma L, Mao F, Liu L, Zhai X, Zhou J Abstract Multifunctional nanomaterials for dual-mode imaging guided cancer therapy are highly desirable in clinical applications. Herein, a flowerlike NiS2-coated NaLuF4:Nd...
Sun Jun 30, 2019 13:53
Related ArticlesStiffness of Aligned Fibers Regulates the Phenotypic Expression of Vascular Smooth Muscle Cells. ACS Appl Mater Interfaces. 2019 Feb 20;11(7):6867-6880 Authors: Yi B, Shen Y, Tang H, Wang X, Li B, Zhang Y Abstract Electrospun uniaxially aligned ultrafine fibers show great promise in constructing vascular grafts mimicking the anisotropic architecture of native blood vessels. However, understanding how the stiffness of aligned fibers would...
Sun Jun 30, 2019 13:53
Related ArticlesComparative Heating Efficiency of Cobalt-, Manganese-, and Nickel-Ferrite Nanoparticles for a Hyperthermia Agent in Biomedicines. ACS Appl Mater Interfaces. 2019 Feb 20;11(7):6858-6866 Authors: Demirci Dönmez ÇE, Manna PK, Nickel R, Aktürk S, van Lierop J Abstract In this study, the ac magnetic hyperthermia responses of spinel CoFe2O4, MnFe2O4, and NiFe2O4 nanoparticles of comparable sizes (∼20 nm) were investigated to evaluate their...
Sun Jun 30, 2019 13:53
Related ArticlesGold Nanoparticle Probe-Assisted Antigen-Counting Chip Using SEM. ACS Appl Mater Interfaces. 2019 Feb 20;11(7):6769-6776 Authors: Zhou X, Yang CT, Xu Q, Lou Z, Xu Z, Thierry B, Gu N Abstract Currently, it remains challenging to count protein-biomarker molecules present in a small droplet of biological samples. Herein, we propose a gold nanoparticle (GNP) probe-assisted sandwich-counting strategy that relies on a GNP probe, an antibody-functionalized...
Sun Jun 30, 2019 13:53
Related ArticlesSustained and Prolonged Delivery of Protein Therapeutics from Two-Dimensional Nanosilicates. ACS Appl Mater Interfaces. 2019 Feb 20;11(7):6741-6750 Authors: Cross LM, Carrow JK, Ding X, Singh KA, Gaharwar AK Abstract We present a nanoengineered system for sustained and prolonged delivery of protein therapeutics, which has the potential to impact current orthopedic regeneration strategies. Specifically, we introduce two-dimensional nanosilicates...
Sun Jun 30, 2019 13:53
Related ArticlesGold Nanocluster-Decorated Nanocomposites with Enhanced Emission and Reactive Oxygen Species Generation. ACS Appl Mater Interfaces. 2019 Feb 20;11(7):7369-7378 Authors: Xia J, Wang X, Zhu S, Liu L, Li L Abstract Ligand-protected gold nanoclusters (AuNCs) show promise for high performance in biological applications, such as imaging and therapeutics. The assembly of AuNCs with biological macromolecules represents a simple but effective...
Sun Jun 30, 2019 13:53
Related ArticlesStimuli-Responsive Conductive Nanocomposite Hydrogels with High Stretchability, Self-Healing, Adhesiveness, and 3D Printability for Human Motion Sensing. ACS Appl Mater Interfaces. 2019 Feb 20;11(7):6796-6808 Authors: Deng Z, Hu T, Lei Q, He J, Ma PX, Guo B Abstract Self-healing, adhesive conductive hydrogels are of great significance in wearable electronic devices, flexible printable electronics, and tissue engineering scaffolds. However,...
Sun Jun 30, 2019 13:53
Related ArticlesFRET-Based Upconversion Nanoprobe Sensitized by Nd3+ for the Ratiometric Detection of Hydrogen Peroxide in Vivo. ACS Appl Mater Interfaces. 2019 Feb 20;11(7):7441-7449 Authors: Wang H, Li Y, Yang M, Wang P, Gu Y Abstract The exorbitant level of hydrogen peroxide is closely related to many human diseases. The development of novel probes for H2O2 detection will be beneficial to disease diagnosis. In this study, a novel Nd3+-sensitized...
Sun Jun 30, 2019 13:53
Related ArticlesStretchable and Highly Sensitive Braided Composite Yarn@Polydopamine@Polypyrrole for Wearable Applications. ACS Appl Mater Interfaces. 2019 Feb 20;11(7):7338-7348 Authors: Pan J, Yang M, Luo L, Xu A, Tang B, Cheng D, Cai G, Wang X Abstract Flexible wearable devices for various applications have attracted research attention in recent years. To date, it is still a big challenge to fabricate strain sensors with a large workable strain range...
Sun Jun 30, 2019 13:53
Related ArticlesRodlike MSN@Au Nanohybrid-Modified Supermolecular Photosensitizer for NIRF/MSOT/CT/MR Quadmodal Imaging-Guided Photothermal/Photodynamic Cancer Therapy. ACS Appl Mater Interfaces. 2019 Feb 20;11(7):6777-6788 Authors: Yang S, You Q, Yang L, Li P, Lu Q, Wang S, Tan F, Ji Y, Li N Abstract Recently, rodlike nanomaterials with specific aspect ratio for efficient cellular uptake have received enormous attention. For functional nanomaterials,...
Sun Jun 30, 2019 13:53
Related ArticlesContact Guidance by Microstructured Gelatin Hydrogels for Prospective Tissue Engineering Applications. ACS Appl Mater Interfaces. 2019 Feb 20;11(7):7450-7458 Authors: Tadsen M, Friedrich RP, Riedel S, Alexiou C, Mayr SG Abstract Design of functionalized biomimetic scaffolds is one of the key approaches for regenerative medicine and other biomedical applications. Development of engineered tissue should optimize organization and function...
Sun Jun 30, 2019 13:53
Related ArticlesAcid-Induced Activated Cell-Penetrating Peptide-Modified Cholesterol-Conjugated Polyoxyethylene Sorbitol Oleate Mixed Micelles for pH-Triggered Drug Release and Efficient Brain Tumor Targeting Based on a Charge Reversal Mechanism. ACS Appl Mater Interfaces. 2018 Dec 19;10(50):43411-43428 Authors: Tian Y, Mi G, Chen Q, Chaurasiya B, Li Y, Shi D, Zhang Y, Webster TJ, Sun C, Shen Y Abstract Glioblastoma multiforme is the most devastating...
Sun Jun 30, 2019 13:53
Related ArticlesTargeted Graphene Oxide Networks: Cytotoxicity and Synergy with Anticancer Agents. ACS Appl Mater Interfaces. 2018 Dec 19;10(50):43523-43532 Authors: Bidram E, Sulistio A, Cho HJ, Amini A, Harris T, Zarrabi A, Qiao G, Stewart A, Dunstan DE Abstract An effective strategy to inhibit endocytosis in cancer cells is presented where modified net-type graphene oxide (GO) sheets, bound with multiple cell surface receptors, are introduced and...
Sun Jun 30, 2019 13:53
Related ArticlesDetection and Imaging of Hydrogen Sulfide in Lysosomes of Living Cells with Activatable Fluorescent Quantum Dots. ACS Appl Mater Interfaces. 2018 Dec 19;10(50):43472-43481 Authors: Wu Y, Wang Q, Wu T, Liu W, Nan H, Xu S, Shen Y Abstract The simple, sensitive, and specific detection of hydrogen sulfide (H2S) is of great importance because of its crucial role in food safety, environmental pollution, and various pathological and physiological...
Sun Jun 30, 2019 13:53
Related ArticlesLong-Circulating Amphiphilic Doxorubicin for Tumor Mitochondria-Specific Targeting. ACS Appl Mater Interfaces. 2018 Dec 19;10(50):43482-43492 Authors: Xi J, Li M, Jing B, An M, Yu C, Pinnock CB, Zhu Y, Lam MT, Liu H Abstract The mitochondria have emerged as a novel target for cancer chemotherapy primarily due to their central roles in energy metabolism and apoptosis regulation. Here, we report a new molecular approach to achieve high...
Sun Jun 30, 2019 13:53
Related ArticlesNovel Fluorescence Switch for MicroRNA Imaging in Living Cells Based on DNAzyme Amplification Strategy. ACS Appl Mater Interfaces. 2018 Dec 19;10(50):43405-43410 Authors: Li P, Wei M, Zhang F, Su J, Wei W, Zhang Y, Liu S Abstract MicroRNAs (miRNAs) play important roles in the regulation of target gene expression and cell development. Therefore, developing of accurate and visual detection methods for miRNAs is important for early diagnosis...
Sun Jun 30, 2019 13:53
Related ArticlesStretchable Triboelectric Textile Composed of Wavy Conductive-Cloth PET and Patterned Stretchable Electrode for Harvesting Multivariant Human Motion Energy. ACS Appl Mater Interfaces. 2018 Dec 19;10(50):43661-43668 Authors: Hou X, Zhu J, Qian J, Niu X, He J, Mu J, Geng W, Xue C, Chou X Abstract Triboelectric textile with wearable property and feasibility of large area preparation has presented a great prospect in effectively collecting...
Sun Jun 30, 2019 13:53
Related ArticlesBioinspired Concentric-Cylindrical Multilayered Scaffolds with Controllable Architectures: Facile Preparation and Biological Applications. ACS Appl Mater Interfaces. 2018 Dec 19;10(50):43512-43522 Authors: Cheng X, Shi H, Wang Z, Zheng G, Liu P, Dai K, Liu C, Shen C Abstract Multilayered objects are the most important and interesting structures in nature, exhibiting multiple functionalities. Inspired by the excellent structural-functional...
Sun Jun 30, 2019 13:53
Related ArticlesDetachable Polyzwitterion-Coated Ternary Nanoparticles Based on Peptide Dendritic Carbon Dots for Efficient Drug Delivery in Cancer Therapy. ACS Appl Mater Interfaces. 2018 Dec 19;10(50):43923-43935 Authors: Ma J, Kang K, Zhang Y, Yi Q, Gu Z Abstract In this work, we presented ternary nanoparticles [poly(carboxybetaine methacrylate) (pCBMA)(peptide dendrimer-modified carbon dots (CD-D)/doxorubicin (DOX))] based on peptide dendritic carbon...
Sun Jun 30, 2019 13:53
Related ArticlesCollagenase-Encapsulated pH-Responsive Nanoscale Coordination Polymers for Tumor Microenvironment Modulation and Enhanced Photodynamic Nanomedicine. ACS Appl Mater Interfaces. 2018 Dec 19;10(50):43493-43502 Authors: Liu J, Tian L, Zhang R, Dong Z, Wang H, Liu Z Abstract The abundant tumor extracellular matrix (ECM) could result in insufficient tumor retention and ineffective intratumor penetration of therapeutic agents as well as an...
Sun Jun 30, 2019 13:53
Related ArticlesCosmetically Adaptable Transparent Strain Sensor for Sensitively Delineating Patterns in Small Movements of Vital Human Organs. ACS Appl Mater Interfaces. 2018 Dec 19;10(50):44126-44133 Authors: Gupta N, Rao KDM, Srivastava K, Gupta R, Kumar A, Marconnet A, Fisher TS, Kulkarni GU Abstract Monitoring live movements of human body parts is becoming increasingly important in the context of biomedical and human machine technologies. The development...
Sun Jun 30, 2019 13:53
Related ArticlesReactive Oxygen Species (ROS)-Responsive Charge-Switchable Nanocarriers for Gene Therapy of Metastatic Cancer. ACS Appl Mater Interfaces. 2018 Dec 19;10(50):43352-43362 Authors: Xiang J, Liu X, Zhou Z, Zhu D, Zhou Q, Piao Y, Jiang L, Tang J, Liu X, Shen Y Abstract The application of nonviral gene vectors has been limited by their insufficient transfection efficiency because of poor serum stability, high endosomal entrapment, limited...
Sun Jun 30, 2019 13:53
Related ArticlesMultifunctional Mechanical Sensors for Versatile Physiological Signal Detection. ACS Appl Mater Interfaces. 2018 Dec 19;10(50):44173-44182 Authors: Pang Y, Yang Z, Han X, Jian J, Li Y, Wang X, Qiao Y, Yang Y, Ren TL Abstract Recently, flexible and wearable mechanical sensors have attracted great attention because of their potential applications in monitoring various physiological signals. However, conventional mechanical sensors rarely...
Sun Jun 30, 2019 13:53
Related ArticlesCoaxial Hydro-Nanofibrils for Self-Assembly of Cell Sheets Producing Skin Bilayers. ACS Appl Mater Interfaces. 2018 Dec 19;10(50):43503-43511 Authors: Mao W, Kang MK, Shin JU, Son YJ, Kim HS, Yoo HS Abstract Bilayered cell sheets were fabricated with coaxial hydro-nanofibrils for three-dimensional (3D) cultivation in a biomimetic environment. Polycaprolactone (PCL) was electrospun and hydrolyzed to release fragmented nanofibrils (NF)...
Sun Jun 30, 2019 13:53
Related ArticlesNatural Sugar-Assisted, Chemically Reinforced, Highly Durable Piezoorganic Nanogenerator with Superior Power Density for Self-Powered Wearable Electronics. ACS Appl Mater Interfaces. 2018 Dec 19;10(50):44018-44032 Authors: Maity K, Garain S, Henkel K, Schmeißer D, Mandal D Abstract Natural piezoelectric materials are of increasing interest, particularly for applications in biocompatible, implantable, and flexible electronic devices....
Sun Jun 30, 2019 13:53
Related ArticlesAn Immuno-Biochip Selectively Captures Tumor-Derived Exosomes and Detects Exosomal RNAs for Cancer Diagnosis. ACS Appl Mater Interfaces. 2018 Dec 19;10(50):43375-43386 Authors: Yang Y, Kannisto E, Yu G, Reid ME, Patnaik SK, Wu Y Abstract Tumor-derived exosomes (TEXs) play instrumental roles in tumor growth, angiogenesis, immune modulation, metastasis, and drug resistance. TEX RNAs are a new class of noninvasive biomarkers for cancer....
Sun Jun 30, 2019 13:53
Related ArticlesTracing Boron with Fluorescence and Positron Emission Tomography Imaging of Boronated Porphyrin Nanocomplex for Imaging-Guided Boron Neutron Capture Therapy. ACS Appl Mater Interfaces. 2018 Dec 19;10(50):43387-43395 Authors: Shi Y, Li J, Zhang Z, Duan D, Zhang Z, Liu H, Liu T, Liu Z Abstract Boron neutron capture therapy (BNCT) induces high-energy radiation within cancer cells while avoiding damage to normal cells without uptake of BNCT...
Sun Jun 30, 2019 13:53
Related ArticlesPaclitaxel-Loaded Core-Shell Magnetic Nanoparticles and Cold Atmospheric Plasma Inhibit Non-Small Cell Lung Cancer Growth. ACS Appl Mater Interfaces. 2018 Dec 19;10(50):43462-43471 Authors: Yu H, Wang Y, Wang S, Li X, Li W, Ding D, Gong X, Keidar M, Zhang W Abstract Nanoparticle-based drug delivery allows effective and sustained delivery of therapeutic agents to solid tumors and has completely changed how cancer is treated. As a new...
Sun Jun 30, 2019 13:53
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