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Τετάρτη 7 Οκτωβρίου 2020

 

Low-grade serous carcinoma (LGSC): A Canadian multicenter review of practice patterns and patient outcomes.
Related Articles Low-grade serous carcinoma (LGSC): A Canadian multicenter review of practice patterns and patient outcomes. Gynecol Oncol. 2020 04;157(1):36-45 Authors: Scott SA, Llaurado Fernandez M, Kim H, Elit L, Nourmoussavi M, Glaze S, Roberts L, Offman SL, Rahimi K, Lytwyn A, Sur M, Gilks CB, Matheson K, Köbel M, Dawson A, Tinker AV, Kwon JS, Hoskins P, Santos JL, Cheung A, Provencher D, Carey MS, Canadian LGSC Community of Practice (GOC-CoP) ...
Rare Cancers
Wed Oct 07, 2020 13:43
Disparities in care among patients with low-grade serous ovarian carcinoma.
Related Articles Disparities in care among patients with low-grade serous ovarian carcinoma. Gynecol Oncol. 2020 04;157(1):46-54 Authors: Siemon J, Galli J, Slomovitz B, Schlumbrecht M Abstract OBJECTIVE: Low-grade serous carcinoma (LGSC) is a rare histotype of ovarian cancer with a unique disease course. Little data exist regarding the influence of sociodemographic factors on diagnosis and outcomes in this disease. Our objective was to evaluate...
Rare Cancers
Wed Oct 07, 2020 13:43
Prognosis of haploidentical hematopoietic stem cell transplantation in non-infant children with t(v;11q23)/MLL-rearranged B-cell acute lymphoblastic leukemia.
Related Articles Prognosis of haploidentical hematopoietic stem cell transplantation in non-infant children with t(v;11q23)/MLL-rearranged B-cell acute lymphoblastic leukemia. Leuk Res. 2020 04;91:106333 Authors: Bai L, Cheng YF, Lu AD, Suo P, Wang Y, Zuo YX, Yan CH, Wu J, Jia YP, Sun YQ, Chen YH, Chen H, Liu KY, Han W, Xu LP, Wang JB, Tang XF, Chen HR, Zhang LP, Huang XJ Abstract B-cell acute lymphoblastic leukemia (B-ALL) with MLL-rearrangements...
Rare Cancers
Wed Oct 07, 2020 13:43
Lymph node metastasis probability in young patients eligible for conservative management of endometrial cancer.
Related Articles Lymph node metastasis probability in young patients eligible for conservative management of endometrial cancer. Gynecol Oncol. 2020 04;157(1):131-135 Authors: Gonthier C, Douhnai D, Koskas M Abstract OBJECTIVE: Endometrial cancer (EC) is a rare condition in young women. The objective of this study was to evaluate the risk of pelvic lymph node (LN) metastasis in young women with EC who are candidates for conservative management....
Rare Cancers
Wed Oct 07, 2020 13:43
Rich Fat Hemangioma of the Parotid Gland in the Adult.
Related Articles Rich Fat Hemangioma of the Parotid Gland in the Adult. J Craniofac Surg. 2020 Jun;31(4):1054-1055 Authors: Liu J, Cheng LJ, Zhang Y, Song TH, Wang JW Abstract Hemangiomas are relatively rare tumors representing approximately 0.4% of all the salivary gland tumors and occur predominantly in the parotid. Most of the hemangiomas appear during the first year of life; however, are uncommon in adults. Moreover, the rich fat hemangiomas...
Rare Cancers
Wed Oct 07, 2020 13:43
Fertility and prognosis of borderline ovarian tumor after conservative management: Results of the multicentric OPTIBOT study by the GINECO & TMRG group.
Related Articles Fertility and prognosis of borderline ovarian tumor after conservative management: Results of the multicentric OPTIBOT study by the GINECO & TMRG group. Gynecol Oncol. 2020 04;157(1):29-35 Authors: Chevrot A, Pouget N, Bats AS, Huchon C, Guyon F, Chopin N, Rousset-Jablonski C, Beurrier F, Lambaudie E, Provansal M, Sabatier R, Heinemann M, Ngo C, Bonsang-Kitzis H, Lecuru F, Bailly E, Ferron G, Cornou C, Lardin E, Leblanc E, Philip CA, Ray-Coquard...
Rare Cancers
Wed Oct 07, 2020 13:43
Lacrimal Gland Hamartoma (Formerly Termed Dacryoadenoma).
Related Articles Lacrimal Gland Hamartoma (Formerly Termed Dacryoadenoma). Am J Ophthalmol. 2020 09;217:189-197 Authors: Milman T, Jakobiec FA, Lally SE, Shields JA, Shields CL, Eagle RC Abstract PURPOSE: Since the original description of "dacryadenoma" by Jakobiec and associates, the data on this unusual epibulbar lacrimal gland lesion remain sparse. The aim of this study was to characterize clinically, morphologically, and immunohistochemically...
Rare Cancers
Wed Oct 07, 2020 13:43
The usefulness of intraoperative neurological monitoring for esophageal cancer with double aortic arch; a case report.
Related Articles The usefulness of intraoperative neurological monitoring for esophageal cancer with double aortic arch; a case report. BMC Surg. 2020 May 04;20(1):86 Authors: Mushiake S, Taniguchi K, Lee SW, Shimizu T, Imai Y, Tanaka R, Honda K, Tashiro K, Kawai M, Uchiyama K Abstract BACKGROUND: Double aortic arch (DAA) is a congenital anomaly of the aorta. Esophageal cancer with DAA is rare, and consequently, the appropriate surgical approach...
Rare Cancers
Wed Oct 07, 2020 13:43
Successful treatment of steroid-refractory immune checkpoint inhibitor-related pneumonitis with triple combination therapy: a case report.
Related Articles Successful treatment of steroid-refractory immune checkpoint inhibitor-related pneumonitis with triple combination therapy: a case report. Cancer Immunol Immunother. 2020 Oct;69(10):2033-2039 Authors: Utsumi H, Araya J, Okuda K, Watanabe J, Takekoshi D, Fujita Y, Hashimoto M, Wakui H, Minagawa S, Numata T, Hara H, Kuwano K Abstract Immune checkpoint inhibitor (ICI)-related pneumonitis is a relatively rare but clinically serious...
Rare Cancers
Wed Oct 07, 2020 13:43
Consecutive single-institution case series of primary central nervous system lymphoma treated by R-MPV or high-dose methotrexate monotherapy.
Related Articles Consecutive single-institution case series of primary central nervous system lymphoma treated by R-MPV or high-dose methotrexate monotherapy. Jpn J Clin Oncol. 2020 Sep 05;50(9):999-1008 Authors: Sasaki N, Kobayashi K, Saito K, Shimizu S, Suzuki K, Lee J, Yamagishi Y, Shibahara J, Takayama N, Shiokawa Y, Nagane M Abstract OBJECTIVE: The optimal regimen for use of high dose-methotrexate-based chemotherapy in primary central...
Rare Cancers
Wed Oct 07, 2020 13:43
Misdiagnosis of a multi-organ involvement hematogenous disseminated tuberculosis as metastasis: a case report and literature review.
Related Articles Misdiagnosis of a multi-organ involvement hematogenous disseminated tuberculosis as metastasis: a case report and literature review. Infect Dis Poverty. 2020 Jun 09;9(1):66 Authors: Hang TX, Fang G, Huang Y, Hu CM, Chen W Abstract BACKGROUND: Tuberculosis (TB) is a great mimicker and diagnostic chameleon, and prone to be diagnosed as malignancy. Even though many reports have described the differences between pulmonary TB and...
Rare Cancers
Wed Oct 07, 2020 13:43
The first case report of polymerase proofreading-associated polyposis in POLD1 variant, c.1433G>A p.S478N, in Japan.
Related Articles The first case report of polymerase proofreading-associated polyposis in POLD1 variant, c.1433G>A p.S478N, in Japan. Jpn J Clin Oncol. 2020 Sep 05;50(9):1080-1083 Authors: Ito T, Nomizu T, Eguchi H, Kamae N, Dechamethakun S, Akama Y, Endo G, Sugano K, Yoshida T, Okazaki Y, Ishida H Abstract Polymerase proofreading-associated polyposis, caused by germline variants in the exonuclease domains of POLD1 and POLE, is a dominantly...
Rare Cancers
Wed Oct 07, 2020 13:43
Risk factors and treatment outcomes of 239 patients with testicular granulosa cell tumors: a systematic review of published case series data.
Related Articles Risk factors and treatment outcomes of 239 patients with testicular granulosa cell tumors: a systematic review of published case series data. J Cancer Res Clin Oncol. 2020 Nov;146(11):2829-2841 Authors: Grogg JB, Schneider K, Bode PK, Kranzbühler B, Eberli D, Sulser T, Beyer J, Lorch A, Hermanns T, Fankhauser CD Abstract PURPOSE: Testicular granulosa cell tumors (tGrCT) are rare sex cord-stromal tumors. This review aims to...
Rare Cancers
Wed Oct 07, 2020 13:43
Primary ovarian carcinoid: Two cases report and review of literature.
Primary ovarian carcinoid: Two cases report and review of literature. Medicine (Baltimore). 2020 Oct 02;99(40):e21109 Authors: Zhai LR, Zhang XW, Yu T, Jiang ZD, Huang DW, Jia Y, Cui MH Abstract INTRODUCTION: Carcinoid tumor is one of the most frequent neuroendocrine tumors, and the majority of which are usually observed in the lungs and gastrointestinal tract. The prevalence of ovarian carcinoids is merely 0.1% in ovarian neoplasms and 1%...
Rare Cancers
Wed Oct 07, 2020 13:43
Characteristics of Cancer Patients in the World Trade Center Environmental Health Center.
Characteristics of Cancer Patients in the World Trade Center Environmental Health Center. Int J Environ Res Public Health. 2020 Oct 01;17(19): Authors: Durmus N, Shao Y, Arslan AA, Zhang Y, Pehlivan S, Fernandez-Beros ME, Umana L, Corona R, Smyth-Giambanco S, Abbott SA, Reibman J Abstract The destruction of the World Trade Center (WTC) towers on 11 September 2001 released many tons of aerosolized dust and smoke with potential for carcinogenic...
Rare Cancers
Wed Oct 07, 2020 13:43
Whole genome, transcriptome and methylome profiling enhances actionable target discovery in high-risk pediatric cancer.
Whole genome, transcriptome and methylome profiling enhances actionable target discovery in high-risk pediatric cancer. Nat Med. 2020 Oct 05;: Authors: Wong M, Mayoh C, Lau LMS, Khuong-Quang DA, Pinese M, Kumar A, Barahona P, Wilkie EE, Sullivan P, Bowen-James R, Syed M, Martincorena I, Abascal F, Sherstyuk A, Bolanos NA, Baber J, Priestley P, Dolman MEM, Fleuren EDG, Gauthier ME, Mould EVA, Gayevskiy V, Gifford AJ, Grebert-Wade D, Strong PA, Manouvrier E, Warby...
Rare Cancers
Wed Oct 07, 2020 13:43
The genetic landscape of metaplastic breast cancers and uterine carcinosarcomas.
The genetic landscape of metaplastic breast cancers and uterine carcinosarcomas. Mol Oncol. 2020 Oct 05;: Authors: Moukarzel L, Ferrando L, Da Cruz Paula A, Brown DN, Geyer FC, Pareja F, Piscuoglio S, Papanastasiou AD, Fusco N, Marchiò C, Abu-Rustum NR, Murali R, Brogi E, Wen HY, Norton L, Soslow RA, Vincent-Salomon A, Reis-Filho JS, Weigelt B Abstract Metaplastic breast carcinoma (MBC) and uterine carcinosarcoma (UCS) are rare aggressive cancers,...
Rare Cancers
Wed Oct 07, 2020 13:43
Primary Squamous Cell Carcinoma of Colon and Rectum: A Systematic Review of the Literature.
Primary Squamous Cell Carcinoma of Colon and Rectum: A Systematic Review of the Literature. J Invest Surg. 2020 Oct 06;:1-6 Authors: Schizas D, Katsaros I, Mastoraki A, Karela NR, Zampetaki D, Lazaridis II, Tsapralis D, Theodoropoulos GE Abstract Background - Objective: Primary colorectal squamous cell carcinoma is an extremely rare neoplasm with an incidence of 0.1 to 0.25 per 1,000 diagnosed colorectal carcinomas.The objective of this study...
Rare Cancers
Wed Oct 07, 2020 13:43
The Value of DICER1 Mutation Analysis in "Subtle" Diagnostically Challenging Embryonal Rhabdomyosarcomas of the Uterine Cervix.
The Value of DICER1 Mutation Analysis in "Subtle" Diagnostically Challenging Embryonal Rhabdomyosarcomas of the Uterine Cervix. Int J Gynecol Pathol. 2020 Oct 05;: Authors: Yoon JY, Apellaniz-Ruiz M, Chong AL, Slim Z, Salfinger SG, Clarke BA, Stewart CJR, Foulkes WD, McCluggage WG Abstract Embryonal rhabdomyosarcoma of the uterine cervix is a rare neoplasm which is almost invariably associated with pathogenic somatic or germline DICER1 mutations;...
Rare Cancers
Wed Oct 07, 2020 13:43
Preoperative Misdiagnosis of Malignant Mucosal Melanoma of the Nasal Septum by MRI.
Preoperative Misdiagnosis of Malignant Mucosal Melanoma of the Nasal Septum by MRI. Ear Nose Throat J. 2020 Oct 06;:145561320963566 Authors: Kim KS, Min HJ Abstract Malignant sinonasal mucosal melanoma is a rare and aggressive neoplasm. As it shows nonspecific clinical symptoms, magnetic resonance imaging (MRI) is the most effective diagnostic tool. Before a mass is histopathologically confirmed, MRI is regarded as the optimal differential...
Rare Cancers
Wed Oct 07, 2020 13:43
Successful Treatment of a Patient with Chronic Myelogenous Leukemia with Concurrent Janus Kinase 2 (JAK2) R795S Mutation and Breakpoint Cluster Region-ABL1 (BCR-ABL1) Fusion: A Case Report and Literature Review.
Successful Treatment of a Patient with Chronic Myelogenous Leukemia with Concurrent Janus Kinase 2 (JAK2) R795S Mutation and Breakpoint Cluster Region-ABL1 (BCR-ABL1) Fusion: A Case Report and Literature Review. Am J Case Rep. 2020 Oct 06;21:e925151 Authors: Yue Y, Wei W, Guo Y, Wang F, Dong W, Liu Y, Lin Y, Cao Y, Gu W Abstract BACKGROUND Although the V617F mutation in the Janus kinase 2 (JAK2) gene and the breakpoint cluster region-abl1 (BCR-ABL1)...
Rare Cancers
Wed Oct 07, 2020 13:43
Desmoid tumors: To treat or not to treat, that is the question.
Desmoid tumors: To treat or not to treat, that is the question. Cancer. 2020 Oct 06;: Authors: Kasper B, Raut CP, Gronchi A Abstract Desmoid tumors (DTs) are a rare disease of intermediate malignancy characterized histologically by a locally aggressive, monoclonal, fibroblastic proliferation and clinically by a variable and often unpredictable course. For decades, surgical resection has been the standard initial treatment approach; however,...
Rare Cancers
Wed Oct 07, 2020 13:43
Negative Estrogen receptors and positive progesterone receptors breast cancers.
Negative Estrogen receptors and positive progesterone receptors breast cancers. J Gynecol Obstet Hum Reprod. 2020 Oct 03;:101928 Authors: Delvallée J, Etienne C, Arbion F, Vildé A, Body G, Ouldamer L Abstract CONTEXT: Hormone receptors (estrogen receptor ER and progesterone receptor PR) are prognostic and predictive factors of outcome for invasive breast cancer. Some tumors only express one of these hormone receptors (ER or PR). ER negative/PR...
Rare Cancers
Wed Oct 07, 2020 13:43
Should triple-positive breast cancer be recognized as a distinct subtype?
Should triple-positive breast cancer be recognized as a distinct subtype? Expert Rev Anticancer Ther. 2020 Oct 06;:1-4 Authors: Dieci MV, Guarneri V PMID: 33021124 [PubMed - as supplied by publisher]
pubmed: expert review of ant...
Wed Oct 07, 2020 13:46
Erythromycin stimulates phasic gastric contractility as assessed with an isovolumetric intragastric balloon pressure measurement
Erythromycin stimulates phasic gastric contractility as assessed with an isovolumetric intragastric balloon pressure measurement. Abstract Background A novel technique to assess gastric motility by measuring the pressure in a low‐volume intragastric balloon was developed to monitor (disordered) motility. We previously showed that this technique allows measuring pharmacologically induced inhibition of motility. In this study, we assessed whether it is possible to measure pharmacologically...
The European Gastrointestinal Motility Society
Tue Oct 06, 2020 18:38
Investigator initiated research in times of COVID‐19: Let’s go digital!
The European Gastrointestinal Motility Society
Tue Oct 06, 2020 19:21
Comparative effectiveness study of chemotherapy in follicular lymphoma patients in the rituximab era: a Japanese claims database study.
Comparative effectiveness study of chemotherapy in follicular lymphoma patients in the rituximab era: a Japanese claims database study. Future Oncol. 2020 Oct 06;: Authors: Tsutsué S, Tobinai K, Yi J, Crawford B Abstract Aim: To evaluate comparative effectiveness of rituximub (R)-based versus non-R-based therapies for follicular lymphoma patients in Japan, where limited studies have been reported. Materials & methods: Patients who received...
Future Oncology.
Wed Oct 07, 2020 13:49
Integrating the melanoma 31-gene expression profile test to surgical oncology practice within national guideline and staging recommendations.
Integrating the melanoma 31-gene expression profile test to surgical oncology practice within national guideline and staging recommendations. Future Oncol. 2020 Oct 06;: Authors: Hyams DM, Covington KR, Johnson CE, Plasseraud KM, Cook RW Abstract Aim: Define changes in clinical management resulting from use of the prognostic 31-gene expression profile (31-GEP) test for cutaneous melanoma in a surgical oncology practice. Patients & methods:...
Future Oncology.
Wed Oct 07, 2020 13:49
Effect of comorbidities/comedications on sunitinib outcomes for metastatic renal cell carcinoma: the STAR-TOR registry.
Effect of comorbidities/comedications on sunitinib outcomes for metastatic renal cell carcinoma: the STAR-TOR registry. Future Oncol. 2020 Oct 06;: Authors: Boegemann M, Schlack K, Rink M, Bernhardt S, Moran M, Hubbe M, Bergmann L, Schmid M, Strauss A Abstract Aim: Examine the effects of baseline hypertension (HTN) and statin or proton pump inhibitor (PPI) use on sunitinib treatment outcomes in STAR-TOR, a real-world registry. Materials &...
Future Oncology.
Wed Oct 07, 2020 13:49
Combination of eribulin plus AKT inhibitor evokes synergistic cytotoxicity in soft tissue sarcoma cells.
Related Articles Combination of eribulin plus AKT inhibitor evokes synergistic cytotoxicity in soft tissue sarcoma cells. Sci Rep. 2019 04 08;9(1):5759 Authors: Hayasaka N, Takada K, Nakamura H, Arihara Y, Kawano Y, Osuga T, Murase K, Kikuchi S, Iyama S, Emori M, Sugita S, Hasegawa T, Takasawa A, Miyanishi K, Kobune M, Kato J Abstract An activated AKT pathway underlies the pathogenesis of soft tissue sarcoma (STS), with over-expressed phosphorylated...
pubmed: cell cycle arrest
Wed Oct 07, 2020 13:57
MDA-MB-157 Cell Line Presents High Levels of MAD2L2 and Dysregulated Mitosis.
MDA-MB-157 Cell Line Presents High Levels of MAD2L2 and Dysregulated Mitosis. Anticancer Res. 2020 Oct;40(10):5471-5480 Authors: Pernicone N, Peretz L, Grinshpon S, Listovsky T Abstract BACKGROUND/AIM: Accurate regulation of the spindle assembly checkpoint (SAC) and anaphase promoting complex/cyclosome (APC/C) are essential for the correct execution of mitosis. In this work, we focused on MAD2L2 (REV7), a central translesion (TLS) protein,...
pubmed: cell cycle arrest
Wed Oct 07, 2020 13:57
Induction of Redox-Mediated Cell Death in ER-Positive and ER-Negative Breast Cancer Cells by a Copper(II)-Phenolate Complex: An In Vitro and In Silico Study.
Induction of Redox-Mediated Cell Death in ER-Positive and ER-Negative Breast Cancer Cells by a Copper(II)-Phenolate Complex: An In Vitro and In Silico Study. Molecules. 2020 Oct 01;25(19): Authors: Periasamy VS, Riyasdeen A, Rajendiran V, Palaniandavar M, Krishnamurthy H, Alshatwi AA, Akbarsha MA Abstract This research was aimed at finding the cytotoxic potential of the mixed ligand copper(II) complex [Cu(tdp)(phen)](ClO4)-where H(tdp)...
pubmed: cell cycle arrest
Wed Oct 07, 2020 13:57
Rewiring of B cell receptor signaling by Epstein-Barr virus LMP2A.
Rewiring of B cell receptor signaling by Epstein-Barr virus LMP2A. Proc Natl Acad Sci U S A. 2020 Oct 05;: Authors: Fish K, Comoglio F, Shaffer AL, Ji Y, Pan KT, Scheich S, Oellerich A, Doebele C, Ikeda M, Schaller SJ, Nguyen H, Muppidi J, Wright GW, Urlaub H, Serve H, Staudt LM, Longnecker R, Oellerich T Abstract Epstein-Barr virus (EBV) infects human B cells and reprograms them to allow virus replication and persistence. One key viral...
pubmed: cell cycle arrest
Wed Oct 07, 2020 13:57
HDAC6 Regulates Radiosensitivity of Non-Small Cell Lung Cancer by Promoting Degradation of Chk1.
HDAC6 Regulates Radiosensitivity of Non-Small Cell Lung Cancer by Promoting Degradation of Chk1. Cells. 2020 Oct 04;9(10): Authors: Moses N, Zhang M, Wu JY, Hu C, Xiang S, Geng X, Chen Y, Bai W, Zhang YW, Bepler G, Zhang XM Abstract We have previously discovered that HDAC6 regulates the DNA damage response (DDR) via modulating the homeostasis of a DNA mismatch repair protein, MSH2, through HDAC6's ubiquitin E3 ligase activity. Here, we...
pubmed: cell cycle arrest
Wed Oct 07, 2020 13:57
Combination therapy of cold atmospheric plasma (CAP) with temozolomide in the treatment of U87MG glioblastoma cells.
Combination therapy of cold atmospheric plasma (CAP) with temozolomide in the treatment of U87MG glioblastoma cells. Sci Rep. 2020 Oct 05;10(1):16495 Authors: Gjika E, Pal-Ghosh S, Kirschner ME, Lin L, Sherman JH, Stepp MA, Keidar M Abstract Cold atmospheric plasma (CAP) technology, a relatively novel technique mainly investigated as a stand-alone cancer treatment method in vivo and in vitro, is being proposed for application in conjunction...
pubmed: cell cycle arrest
Wed Oct 07, 2020 13:57
Long intergenic noncoding RNA 00908 promotes proliferation and inhibits apoptosis of colorectal cancer cells by regulating KLF5 expression.
Long intergenic noncoding RNA 00908 promotes proliferation and inhibits apoptosis of colorectal cancer cells by regulating KLF5 expression. J Cell Physiol. 2020 Jul 06;: Authors: Shan TD, Tian ZB, Li Q, Jiang YP, Liu FG, Sun XG, Han Y, Sun LJ, Chen L Abstract Long intergenic noncoding RNAs (lincRNAs) play a vital role in the occurrence and progression of cancer. The mechanism of lincRNAs in colorectal cancer (CRC) has not been fully elucidated....
pubmed: cell cycle arrest
Wed Oct 07, 2020 13:57
Autophagy displays divergent roles during intermittent amino acid starvation and toxic stress-induced senescence in cultured skeletal muscle cells.
Autophagy displays divergent roles during intermittent amino acid starvation and toxic stress-induced senescence in cultured skeletal muscle cells. J Cell Physiol. 2020 Oct 06;: Authors: Bloemberg D, Quadrilatero J Abstract Due to the ever-expanding functions attributed to autophagy, there is widespread interest in understanding its contribution to human physiology; however, its specific cellular role as a stress-response mechanism is...
pubmed: cell cycle arrest
Wed Oct 07, 2020 13:57
MicroRNAs are critical regulators of senescence and aging in mesenchymal stem cells.
MicroRNAs are critical regulators of senescence and aging in mesenchymal stem cells. Bone. 2020 Oct 03;:115679 Authors: Potter M, Hill WD, Isales CM, Hamrick MW, Fulzele S Abstract MicroRNAs (miRNAs) have recently come under scrutiny for their role in various age-related diseases. Similarly, cellular senescence has been linked to disease and aging. MicroRNAs and senescence likely play an intertwined role in driving these pathologic states....
pubmed: cell cycle arrest
Wed Oct 07, 2020 13:57
Development of triazolothiadiazine derivatives as highly potent tubulin polymerization inhibitors: Structure-activity relationship, in vitro and in vivo study.
Development of triazolothiadiazine derivatives as highly potent tubulin polymerization inhibitors: Structure-activity relationship, in vitro and in vivo study. Eur J Med Chem. 2020 Sep 18;208:112847 Authors: Ma W, Chen P, Huo X, Ma Y, Li Y, Diao P, Yang F, Zheng S, Hu M, You W, Zhao P Abstract Based on our prior work, we reported the design, synthesis, and biological evaluation of fifty-two new triazolothiadiazine-based analogues of CA-4...
pubmed: cell cycle arrest
Wed Oct 07, 2020 13:57
In Vitro Anticancer Effects of All-trans Retinoic Acid in Combination with Dacarbazine against CD117+ Melanoma Cells.
In Vitro Anticancer Effects of All-trans Retinoic Acid in Combination with Dacarbazine against CD117+ Melanoma Cells. Drug Res (Stuttg). 2020 Oct 06;: Authors: Jobani BM, Mohebi E, Najafzadeh N Abstract BACKGROUND: Malignant melanoma is a common form of skin cancer that contains different cell types recognized by various cell surface markers. Dacarbazine-based combination chemotherapy is frequently used for the treatment of melanoma. Despite...
pubmed: cell cycle arrest
Wed Oct 07, 2020 13:57
Facteurs prédictifs des séquelles de paralysie faciale idiopathique : suivi longitudinal
Publication date: Available online 6 October 2020Source: Annales de Chirurgie Plastique EsthétiqueAuthor(s): D. Picard, R. Leroy, T. Poussy, F. Tankéré, P. Gatignol
Plastique Esthétique
Wed Oct 07, 2020 14:02
Construct and Discriminant Validity of the Persian Version of the Consensus Auditory Perceptual Evaluation of Voice (CAPE-V)
Publication date: Available online 6 October 2020Source: Journal of VoiceAuthor(s): Payman Dabirmoghaddam, Hassan Khoramshahi, Ali Dehqan, Ronald C Scherer, Noureddin Nakhostin Ansari
Voice
Wed Oct 07, 2020 14:05
Determination of the Voice Parameters in Adult Individuals With Rheumatoid Arthritis and the Relation of Voice With Depression and Inflammation
Publication date: Available online 7 October 2020Source: Journal of VoiceAuthor(s): Elif Tunç Songur, Alper Kutalmış Türkcan, Hazan Karadeniz, Aslıhan Avanoğlu Güler, Dilek Yapar, Mehmet Akif Öztürk, Metin Yılmaz
Voice
Wed Oct 07, 2020 14:05
(To) Zoom Dread
Journal of Cutaneous Medicine and Surgery, Volume 24, Issue 5, Page 451-452, September/October 2020.
SAGE Publications Inc: Journal of Cutaneous Medicine and Surgery: Table of Contents
Wed Oct 07, 2020 11:00
Visual Dermatology: Sustained Remission of Richter’s Syndrome
Journal of Cutaneous Medicine and Surgery, Volume 24, Issue 5, Page 520-520, September/October 2020.
SAGE Publications Inc: Journal of Cutaneous Medicine and Surgery: Table of Contents
Wed Oct 07, 2020 11:02
Visual Dermatology: Dermatosis Neglecta or Unwashed Dermatosis
Journal of Cutaneous Medicine and Surgery, Volume 24, Issue 5, Page 518-518, September/October 2020.
SAGE Publications Inc: Journal of Cutaneous Medicine and Surgery: Table of Contents
Wed Oct 07, 2020 11:02
Visual Dermatology: Hemorrhagic Bulla in Oral Cavity
Journal of Cutaneous Medicine and Surgery, Volume 24, Issue 5, Page 519-519, September/October 2020.
SAGE Publications Inc: Journal of Cutaneous Medicine and Surgery: Table of Contents
Wed Oct 07, 2020 11:02
Digital Breast Tomosynthesis Slab Thickness: Impact on Reader Performance and Interpretation Time.
Digital Breast Tomosynthesis Slab Thickness: Impact on Reader Performance and Interpretation Time. Radiology. 2020 Oct 06;:192805 Authors: Pujara AC, Joe AI, Patterson SK, Neal CH, Noroozian M, Ma T, Chan HP, Helvie MA, Maturen KE Abstract Background Digital breast tomosynthesis (DBT) helps reduce recall rates and improve cancer detection compared with two-dimensional (2D) mammography but has a longer interpretation time. Purpose To evaluate...
Radiology
Wed Oct 07, 2020 14:14
MRI Findings of Liver Parenchyma Peripheral to Colorectal Liver Metastasis: A Potential Predictor of Long-term Prognosis.
MRI Findings of Liver Parenchyma Peripheral to Colorectal Liver Metastasis: A Potential Predictor of Long-term Prognosis. Radiology. 2020 Oct 06;:202367 Authors: Nakai Y, Gonoi W, Kurokawa R, Nishioka Y, Abe H, Arita J, Ushiku T, Hasegawa K, Abe O Abstract Background Gadoxetic acid (Gd-EOB-DTPA)-enhanced MRI is superior to CT in the detection of colorectal liver metastases (CRLMs) smaller than 10 mm. However, few studies have used MRI...
Radiology
Wed Oct 07, 2020 14:14
Management of Nodules Attached to the Costal Pleura at Low-Dose CT Screening for Lung Cancer.
Management of Nodules Attached to the Costal Pleura at Low-Dose CT Screening for Lung Cancer. Radiology. 2020 Oct 06;:202388 Authors: Zhu Y, Yip R, You N, Henschke CI, Yankelevitz DF Abstract Background Pulmonary nodule features have been used to differentiate benign from malignant nodules. Purpose To determine the frequency of solid noncalcified nodules attached to the costal pleura (CP-NCNs) at baseline low-dose CT and to identify key...
Radiology
Wed Oct 07, 2020 14:14
Image-guided Percutaneous Fixation with Internal Cemented Screws of Impending Femoral Neck Pathologic Fractures in Patients with Metastatic Cancer: Safety, Efficacy, and Durability.
Image-guided Percutaneous Fixation with Internal Cemented Screws of Impending Femoral Neck Pathologic Fractures in Patients with Metastatic Cancer: Safety, Efficacy, and Durability. Radiology. 2020 Oct 06;:201341 Authors: Dassa M, Roux C, Tselikas L, Delpla A, Yevich S, Faron M, Teriitehau C, Hakime A, Al Ahmar M, de Baère T, Deschamps F Abstract Background Prophylactic image-guided procedures performed by interventional radiologists for...
Radiology
Wed Oct 07, 2020 14:14
Artificial Intelligence in Low- and Middle-Income Countries: Innovating Global Health Radiology.
Artificial Intelligence in Low- and Middle-Income Countries: Innovating Global Health Radiology. Radiology. 2020 Oct 06;:201434 Authors: Mollura DJ, Culp MP, Pollack E, Battino G, Scheel JR, Mango VL, Elahi A, Schweitzer A, Dako F Abstract Scarce or absent radiology resources impede adoption of artificial intelligence (AI) for medical imaging by resource-poor health institutions. They face limitations in local equipment, personnel expertise,...
Radiology
Wed Oct 07, 2020 14:14
Debate of Chest CT and RT-PCR Test for the Diagnosis of COVID-19.
Debate of Chest CT and RT-PCR Test for the Diagnosis of COVID-19. Radiology. 2020 Oct 06;:203627 Authors: Şendur HN PMID: 33021896 [PubMed - as supplied by publisher]
Radiology
Wed Oct 07, 2020 14:14
Add-on effect of clarithromycin to oral steroids as post- operative therapy for chronic rhinosinusitis with nasal polyps: a randomised controlled trial.
Add-on effect of clarithromycin to oral steroids as post- operative therapy for chronic rhinosinusitis with nasal polyps: a randomised controlled trial. Rhinology. 2020 Oct 06;: Authors: Lin CF, Wang MC, Merton AT, Ho NH, Wu PS, Hsu AT, Wang YP Abstract BACKGROUND: Evidence is lacking regarding the efficacy of macrolides and oral corticosteroids in chronic rhinosinusitis with nasal polyps (CRSwNP) after endoscopic sinus surgery (ESS). Therefore,...
Rhinology
Wed Oct 07, 2020 14:20
The influence of 12-week dance intervention on sleep quality and pain among women with breast cancer – pilot study of a non-randomized clinical trial
Publication date: Available online 6 October 2020Source: Journal of Bodywork and Movement TherapiesAuthor(s): Jayani Sagaz Hiansdt, Leonessa Boing, Fabiana Flores Sperandio, Tatiana de Bem Fretta, Adriana Coutinho de Azevedo Guimarães
ScienceDirect Publication: Journal of Bodywork and Movement Therapies
Wed Oct 07, 2020 14:21
Global physiotherapy approach to thoracolumbar junction syndrome. A case report
Publication date: Available online 7 October 2020Source: Journal of Bodywork and Movement TherapiesAuthor(s): Yvan Ségui, Jose Ramírez-Moreno
ScienceDirect Publication: Journal of Bodywork and Movement Therapies
Wed Oct 07, 2020 14:21
Over-under cartilage tympanoplasty: technique, results and a call for improved reporting.
Over-under cartilage tympanoplasty: technique, results and a call for improved reporting. J Laryngol Otol. 2020 Oct 06;:1-7 Authors: Erbele ID, Fink MR, Mankekar G, Son LS, Mehta R, Arriaga MA Abstract OBJECTIVE: This study aimed to describe the microscopic over-under cartilage tympanoplasty technique, provide hearing results and detail clinically significant complications. METHOD: This was a retrospective case series chart review...
The Journal of laryngology and otology http://goo.gl/Tl02xD
Wed Oct 07, 2020 14:24
Superficial anatomy of the neonatal cerebrum — an ultrasonographic roadmap
Abstract Neurosonography is an essential imaging modality for assessing the neonatal brain, particularly as a screening tool to evaluate intracranial hemorrhage, hydrocephalus and periventricular leukomalacia. The primary advantages of neurosonography include portability, accessibility and lack of ionizing radiation. Its main limitations are intrinsic operator dependence and the need for an open fontanelle. Neurosonographic imaging acquisition is typically performed by placing...
Pediatric Radiology
Wed Oct 07, 2020 03:00
Future Oncology; +34 new citations
34 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: Future Oncology These pubmed results were generated on 2020/10/07PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
pubmed: future oncology
Wed Oct 07, 2020 13:38
Future Oncology; +34 new citations
34 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: Future Oncology These pubmed results were generated on 2020/10/07PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
pubmed: future oncology
Wed Oct 07, 2020 14:38
An Unusual Collection: Nasal Septal Abscess Secondary to a Furuncle.
An Unusual Collection: Nasal Septal Abscess Secondary to a Furuncle. Ear Nose Throat J. 2020 Oct 06;:145561320961197 Authors: Maharaj S, Bhaga H PMID: 33021836 [PubMed - as supplied by publisher]
ear nose throat
Wed Oct 07, 2020 14:39
Preoperative Misdiagnosis of Malignant Mucosal Melanoma of the Nasal Septum by MRI.
Preoperative Misdiagnosis of Malignant Mucosal Melanoma of the Nasal Septum by MRI. Ear Nose Throat J. 2020 Oct 06;:145561320963566 Authors: Kim KS, Min HJ Abstract Malignant sinonasal mucosal melanoma is a rare and aggressive neoplasm. As it shows nonspecific clinical symptoms, magnetic resonance imaging (MRI) is the most effective diagnostic tool. Before a mass is histopathologically confirmed, MRI is regarded as the optimal differential...
ear nose throat
Wed Oct 07, 2020 14:39
An Unhappy Shooting Star: A Laryngeal Foreign Body Masquerading as Croup.
An Unhappy Shooting Star: A Laryngeal Foreign Body Masquerading as Croup. Ear Nose Throat J. 2020 Oct 06;:145561320962585 Authors: Hosokawa S PMID: 33021838 [PubMed - as supplied by publisher]
ear nose throat
Wed Oct 07, 2020 14:39
Evaluating YouTube as a Source of Patient Information for Functional Endoscopic Sinus Surgery.
Evaluating YouTube as a Source of Patient Information for Functional Endoscopic Sinus Surgery. Ear Nose Throat J. 2020 Oct 06;:145561320962867 Authors: Wu V, Lee DJ, Vescan A, Lee JM Abstract OBJECTIVE: To evaluate the quality of information presented on YouTube regarding functional endoscopic sinus surgery (FESS) for patients. METHODS: YouTube was searched using FESS-specific keywords under the setting of "relevance." The first...
ear nose throat
Wed Oct 07, 2020 14:39
Risk factors associated with suicide among hepatocellular carcinoma patients: A surveillance, epidemiology, and end results analysis
Publication date: Available online 7 October 2020Source: European Journal of Surgical OncologyAuthor(s): Chongfa Chen, Yi Jiang, Fang Yang, Qiucheng Cai, Jianyong Liu, Yushen Wu, Huapeng Lin
European Journal of Surgical Oncology (EJSO)
Wed Oct 07, 2020 14:39
Ocular Toxicology: Synergism of UV Radiation and Benzalkonium Chloride.
Ocular Toxicology: Synergism of UV Radiation and Benzalkonium Chloride. Cutan Ocul Toxicol. 2020 Oct 05;:1-27 Authors: Xu M, Sivak JG, McCanna DJ Abstract Purpose: To investigate the combined toxic effect of ultraviolet (UV) radiation and benzalkonium chloride (BAK), a common preservative in ophthalmic eye drops, on human corneal epithelial cells (HCEC).Methods: Cultured HCEC were exposed to different combined and separate UV (280-400 nm) and...
low levels of ultrav...
Wed Oct 07, 2020 14:42
Clinical characteristics and prognosis of elderly nasopharyngeal carcinoma patients receiving intensity-modulated radiotherapy.
Clinical characteristics and prognosis of elderly nasopharyngeal carcinoma patients receiving intensity-modulated radiotherapy. Eur Arch Otorhinolaryngol. 2020 Oct 06;: Authors: Lyu Y, Ni M, Zhai R, Kong F, Du C, Hu C, Ying H Abstract PURPOSE: To evaluate the clinical characteristics and prognosis of elderly nasopharyngeal carcinoma (NPC) patients receiving intensity-modulated radiotherapy (IMRT). METHODS: From June 2008 to October...
http://link.springer.com/journal/405,European archives of oto-rhino-laryngology,The European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino
Wed Oct 07, 2020 14:47
Online Liver Imaging Course; Pivoting to Transform Radiology Education During the SARS-CoV-2 Pandemic
Publication date: Available online 6 October 2020Source: Academic RadiologyAuthor(s): Khaled M Elsayes, Robert M Marks, Serageldin Kamel, Alexander J Towbin, Ania Z Kielar, Parth Patel, Victoria Chernyak, Kathryn J Fowler, Sameh Nassar, Moataz A Soliman, Aya Kamaya, Mishal Mendiratta-Lala, Amir A. Borhani, David T. Fetzer, Alice W Fung, Richard K G Do, Mustafa R Bashir, James Lee, Nikita Consul, Richard Olmsted
Academic Radiology
Wed Oct 07, 2020 14:48
Continued Validation of Ultrasound Guidance Targeting Tasks: Relationship with Procedure Performance
Publication date: Available online 7 October 2020Source: Academic RadiologyAuthor(s): Joshua Franklin Nitsche, Sarah Conrad, Sarah Hoopes, Meredith Carrel, Katherine Bebeau, Brian C. Brost
Academic Radiology
Wed Oct 07, 2020 14:48
Seizing the Teachable Moment — Lessons from Eisenhower’s Heart Attack
New England Journal of Medicine, Ahead of Print.
Massachusetts Medical Society: New England Journal of Medicine: Table of Contents
Tue Oct 06, 2020 12:00
Mixed-type intraductal papillary mucinous neoplasm: Tailored surgical planning - case report.
Mixed-type intraductal papillary mucinous neoplasm: Tailored surgical planning - case report. Int J Surg Case Rep. 2020 Sep 24;76:111-115 Authors: Bassaneze T, Laham AY, Gomes LGL, Coelho BQ, Martinez CAR Abstract INTRODUCTION: With the greater availability of imaging exams, the diagnosis of intraductal papillary mucinous neoplasms (IPMNs) has increased recently. However, there are still questions about adequate management approaches for this...
pubmed: "int j surg case rep...
Wed Oct 07, 2020 15:14
ENTPDases from Pathogenic Trypanosomatids and Purinergic Signaling: shedding light towards Biotechnological Applications.
ENTPDases from Pathogenic Trypanosomatids and Purinergic Signaling: shedding light towards Biotechnological Applications. Curr Top Med Chem. 2020 Oct 05;: Authors: da Silva W, da Rocha Torres N, de Melo Agripino J, da Silva VHF, de Souza ACA, Ribeiro IC, de Oliveira TA, de Souza LA, Andrade LKR, de Moraes JVB, Diogo MA, de Castro RB, Polêto MD, Afonso LCC, Fietto JLR Abstract ENTPDases are enzymes known for hydrolyzing extracellular nucleotides...
Current topics in medicinal chemistry
Wed Oct 07, 2020 15:15
Topical treatment with a mu opioid receptor agonist alleviates corneal allodynia and corneal nerve sensitization in mice
Publication date: December 2020Source: Biomedicine & Pharmacotherapy, Volume 132Author(s): Fanny Joubert, Adrian Guerrero-Moreno, Darine Fakih, Elodie Reboussin, Claire Gaveriaux-Ruff, Maria Carmen Acosta, Juana Gallar, José Alain Sahel, Laurence Bodineau, Christophe Baudouin, William Rostène, Stéphane Mélik-Parsadaniantz, Annabelle Réaux-Le Goazigo
Biomedicine & Pharmacotherapy
Wed Oct 07, 2020 15:19
Natural carbon-based quantum dots and their applications in drug delivery: A review
Publication date: December 2020Source: Biomedicine & Pharmacotherapy, Volume 132Author(s): Akhila Nair, Jozef T. Haponiuk, Sabu Thomas, Sreeraj Gopi
Biomedicine & Pharmacotherapy
Wed Oct 07, 2020 15:19
A review on the efficacy and mechanism of action of Shenkang injection against chronic kidney disease
Publication date: December 2020Source: Biomedicine & Pharmacotherapy, Volume 132Author(s): Jun-Ju Zou, Xiao-Tao Zhou, Yan-Kun Chen, Jia-Lu Liu, Cheng Wang, Yue-Rong Ma, Li Wang
Biomedicine & Pharmacotherapy
Wed Oct 07, 2020 15:19
microRNA-based autophagy inhibition as targeted therapy in pancreatic cancer
Publication date: December 2020Source: Biomedicine & Pharmacotherapy, Volume 132Author(s): Sanhong Liang, Xin Li, Chao Gao, Lexing Zhang
Biomedicine & Pharmacotherapy
Wed Oct 07, 2020 15:19
ASBT(SLC10A2): A promising target for treatment of diseases and drug discovery
Publication date: December 2020Source: Biomedicine & Pharmacotherapy, Volume 132Author(s): Na Yang, Ya-Qian Dong, Guo-Xiang Jia, Si-Miao Fan, Shan-Ze Li, Shen-Shen Yang, Yu-Bo Li
Biomedicine & Pharmacotherapy
Wed Oct 07, 2020 15:19
Anti-tumor activities and mechanisms of Traditional Chinese medicines formulas: A review
Publication date: December 2020Source: Biomedicine & Pharmacotherapy, Volume 132Author(s): Yuqi Fan, Zhe Ma, LuLu Zhao, Wei Wang, Mengyuan Gao, Xiaohua Jia, Huizi Ouyang, Jun He
Biomedicine & Pharmacotherapy
Wed Oct 07, 2020 15:19
Comparative effects of commonly used intraocular dyes on the viability of human retina Müller cells
Publication date: December 2020Source: Biomedicine & Pharmacotherapy, Volume 132Author(s): Yu Shen, Luyi Zhang, Huihui Zhou, Miaoqin Wu
Biomedicine & Pharmacotherapy
Wed Oct 07, 2020 15:19

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