Cancers, Vol. 12, Pages 1755: Roles of NK Cell Receptors 2B4 (CD244), CS1 (CD319), and LLT1 (CLEC2D) in Cancer Cancers doi: 10.3390/cancers12071755 Authors: Casey W. Buller Porunelloor A. Mathew Stephen O. Mathew Natural killer (NK) cells play a pivotal role in the immune system, especially in the recognition and clearance of cancer cells and infected cells. Their effector function is controlled by a delicate balance between the activating and inhibitory signals. We have identified...
Wed Jul 01, 2020 03:00
Cancers, Vol. 12, Pages 1756: Long-Pentraxin 3 Affects Primary Cilium in Zebrafish Embryo and Cancer Cells via the FGF System Cancers doi: 10.3390/cancers12071756 Authors: Jessica Guerra Paola Chiodelli Chiara Tobia Claudia Gerri Marco Presta Primary cilium drives the left-right asymmetry process during embryonic development. Moreover, its dysregulation contributes to cancer progression by affecting various signaling pathways. The fibroblast growth factor (FGF)/FGF receptor...
Wed Jul 01, 2020 03:00
Cancers, Vol. 12, Pages 1751: Protective Effects of Dietary Grape on UVB-Mediated Cutaneous Damages and Skin Tumorigenesis in SKH-1 Mice Cancers doi: 10.3390/cancers12071751 Authors: Charlotte A. Mintie Anna K. Musarra Chandra K. Singh Mary A. Ndiaye Ruth Sullivan Jens C. Eickhoff Nihal Ahmad Non-melanoma skin cancers (NMSCs) are the most diagnosed cancers in the US and occur more frequently in males. We previously demonstrated chemoprotective effects of dietary grape...
Wed Jul 01, 2020 03:00
Cancers, Vol. 12, Pages 1753: Ceramide Synthase 5 Deficiency Aggravates Dextran Sodium Sulfate-Induced Colitis and Colon Carcinogenesis and Impairs T-Cell Activation Cancers doi: 10.3390/cancers12071753 Authors: Khadija El-Hindi Sebastian Brachtendorf Jennifer Christina Hartel Stephanie Oertel Kerstin Birod Sandra Trautmann Dominique Thomas Thomas Ulshöfer Andreas Weigert Olaf Utermöhlen Martin Krönke Sabine Grösch Ceramide synthase 5 is one of six enzymes...
Wed Jul 01, 2020 03:00
Cancers, Vol. 12, Pages 1754: Circulating Cell-Free DNA-Based Liquid Biopsy Markers for the Non-Invasive Prognosis and Monitoring of Metastatic Pancreatic Cancer Cancers doi: 10.3390/cancers12071754 Authors: Marta Toledano-Fonseca M. Teresa Cano Elizabeth Inga Rosa Rodríguez-Alonso M. Auxiliadora Gómez-España Silvia Guil-Luna Rafael Mena-Osuna Juan R. de la de la Haba-Rodríguez Antonio Rodríguez-Ariza Enrique Aranda Liquid biopsy may assist in the management...
Wed Jul 01, 2020 03:00
Cancers, Vol. 12, Pages 1752: Immunotherapy in Prostate Cancer Cancers doi: 10.3390/cancers12071752 Authors: Emily K. Fay Julie N. Graff Immunotherapy encompasses a wide range of therapies to engage the immune system to target malignancies. In recent years, immunotherapy has made a major impact on treatment of metastatic cancer and has altered standard of care for many tumor types. However, predicting and understanding responses across tumor types has been challenging. While some...
Wed Jul 01, 2020 03:00
Cancers, Vol. 12, Pages 1749: Treatment of Locally Advanced Gastric Cancer (LAGC): Back to Lauren’s Classification in Pan–Cancer Analysis Era? Cancers doi: 10.3390/cancers12071749 Authors: Ina Valeria Zurlo Michele Basso Antonia Strippoli Maria Alessandra Calegari Armando Orlandi Alessandra Cassano Mariantonietta Di Di Salvatore Giovanna Garufi Emilio Bria Giampaolo Tortora Carlo Barone Carmelo Pozzo Background: Guidelines recommend a perioperative approach...
Wed Jul 01, 2020 03:00
Cancers, Vol. 12, Pages 1750: Renal and Cardiovascular Toxicities by New Systemic Treatments for Prostate Cancer Cancers doi: 10.3390/cancers12071750 Authors: Giuseppe Saltalamacchia Mara Frascaroli Antonio Bernardo Erica Quaquarini Prostate cancer (PC) is the most common male cancer in Western Countries. In recent years, the treatment of relapsed or metastatic disease had benefited by the introduction of a variety of new different drugs. In consideration of the relative long...
Wed Jul 01, 2020 03:00
Cancers, Vol. 12, Pages 1747: Gene Pair Correlation Coefficients in Sphingolipid Metabolic Pathway as a Potential Prognostic Biomarker for Breast Cancer Cancers doi: 10.3390/cancers12071747 Authors: Meena Kishore Sakharkar Sarinder Kaur Dhillon Saravana Babu Chidambaram Musthafa Mohamed Essa Jian Yang Complex diseases such as cancer are usually governed by dynamic and simultaneous modifications of multiple genes. Since sphingolipids are potent bioactive molecules and regulate...
Wed Jul 01, 2020 03:00
Cancers, Vol. 12, Pages 1748: Reactive Oxygen Species and Antitumor Immunity—From Surveillance to Evasion Cancers doi: 10.3390/cancers12071748 Authors: Andromachi Kotsafti Marco Scarpa Ignazio Castagliuolo Melania Scarpa The immune system is a crucial regulator of tumor biology with the capacity to support or inhibit cancer development, growth, invasion and metastasis. Emerging evidence show that reactive oxygen species (ROS) are not only mediators of oxidative stress but also...
Wed Jul 01, 2020 03:00
Cells, Vol. 9, Pages 1600: Loss of ZC4H2 and RNF220 Inhibits Neural Stem Cell Proliferation and Promotes Neuronal Differentiation Cells doi: 10.3390/cells9071600 Authors: Longlong Zhang Maosen Ye Liang Zhu Jingmei Cha Chaocui Li Yong-Gang Yao Bingyu Mao The ubiquitin E3 ligase RNF220 and its co-factor ZC4H2 are required for multiple neural developmental processes through different targets, including spinal cord patterning and the development of the cerebellum and the...
Wed Jul 01, 2020 03:00
Cells, Vol. 9, Pages 1598: ROS Mediate xCT-Dependent Cell Death in Human Breast Cancer Cells under Glucose Deprivation Cells doi: 10.3390/cells9071598 Authors: Mei-Chun Chen Li-Lin Hsu Sheng-Fan Wang Chih-Yi Hsu Hsin-Chen Lee Ling-Ming Tseng xCT, also known as solute carrier family 7 member 11 (SLC7A11), the light chain of the cystine/glutamate antiporter, is positively correlated with cancer progression due to antioxidant function. During glucose deprivation, the overexpression...
Wed Jul 01, 2020 03:00
Cells, Vol. 9, Pages 1594: Circulating Tumor Cell Migration Requires Fibronectin Acting through Integrin B1 or SLUG Cells doi: 10.3390/cells9071594 Authors: Jeannette Huaman Olorunseun O. Ogunwobi Fibronectin (FN1) is an extracellular matrix protein gaining increasing attention for its multifaceted roles in cancer progression. Using our recently established circulating tumor cell (CTC) lines, we had demonstrated increased FN1 expression and enhanced migration in CTC lines, in comparison...
Wed Jul 01, 2020 03:00
Cells, Vol. 9, Pages 1593: DNA Damage- But Not Enzalutamide-Induced Senescence in Prostate Cancer Promotes Senolytic Bcl-xL Inhibitor Sensitivity Cells doi: 10.3390/cells9071593 Authors: Nicolas Malaquin Arthur Vancayseele Sophie Gilbert Laureen Antenor-Habazac Marc-Alexandre Olivier Zakia Ait Ali Brahem Fred Saad Guila Delouya Francis Rodier Cellular senescence is a natural tumor suppression mechanism defined by a stable proliferation arrest. In the context of...
Wed Jul 01, 2020 03:00
Cells, Vol. 9, Pages 1599: Chemerin Impairs In Vitro Testosterone Production, Sperm Motility, and Fertility in Chicken: Possible Involvement of Its Receptor CMKLR1 Cells doi: 10.3390/cells9071599 Authors: Anthony Estienne Maxime Reverchon Agnieszka Partyka Guillaume Bourdon Jérémy Grandhaye Alix Barbe Erika Caldas-Silveira Christelle Rame Wojciech Niżański Pascal Froment Joelle Dupont The chemokine chemerin is a novel adipokine involved in the regulation...
Wed Jul 01, 2020 03:00
Cells, Vol. 9, Pages 1595: Microglia Purinoceptor P2Y6: An Emerging Therapeutic Target in CNS Diseases Cells doi: 10.3390/cells9071595 Authors: Shehata Anwar Vincent Pons Serge Rivest The purinergic receptor P2Y6 is expressed in immune cells, including the microglia that are implicated in neurological disorders. Its ligand, UDP, is a signaling molecule that can serve as an “find-me” signal when released in significant quantities by damaged/dying cells. The binding...
Wed Jul 01, 2020 03:00
Cells, Vol. 9, Pages 1591: All-Trans Retinoic Acid Enhances Both the Signaling for Priming and the Glycolysis for Activation of NLRP3 Inflammasome in Human Macrophage Cells doi: 10.3390/cells9071591 Authors: Ahmad Alatshan Gergő E. Kovács Azzam Aladdin Zsolt Czimmerer Krisztina Tar Szilvia Benkő All-trans retinoic acid (ATRA) is a derivative of vitamin A that has many important biological functions, including the modulation of immune responses. ATRA actions are mediated...
Wed Jul 01, 2020 03:00
Cells, Vol. 9, Pages 1596: Exploring Therapeutic Targets to Reverse or Prevent the Transition from Metabolically Healthy to Unhealthy Obesity Cells doi: 10.3390/cells9071596 Authors: Tenzin D. Dagpo Christopher J. Nolan Viviane Delghingaro-Augusto The prevalence of obesity and obesity-related metabolic comorbidities are rapidly increasing worldwide, placing a huge economic burden on health systems. Excessive nutrient supply combined with reduced physical exercise results in positive...
Wed Jul 01, 2020 03:00
Cells, Vol. 9, Pages 1592: Targeted Brain Tumor Therapy by Inhibiting the MDM2 Oncogene: In Vitro and In Vivo Antitumor Activity and Mechanism of Action Cells doi: 10.3390/cells9071592 Authors: Surendra R. Punganuru Viswanath Artula Wei Zhao Mehrdad Rajaei Hemantkumar Deokar Ruiwen Zhang John K. Buolamwini Kalkunte S. Srivenugopal Wei Wang There is a desperate need for novel and efficacious chemotherapeutic strategies for human brain cancers. There are abundant...
Wed Jul 01, 2020 03:00
Cells, Vol. 9, Pages 1590: Non-Muscle Myosin 2A (NM2A): Structure, Regulation and Function Cells doi: 10.3390/cells9071590 Authors: Cláudia Brito Sandra Sousa Non-muscle myosin 2A (NM2A) is a motor cytoskeletal enzyme with crucial importance from the early stages of development until adulthood. Due to its capacity to convert chemical energy into force, NM2A powers the contraction of the actomyosin cytoskeleton, required for proper cell division, adhesion and migration, among other...
Wed Jul 01, 2020 03:00
Cells, Vol. 9, Pages 1597: Chemically Functionalized Water-Soluble Single-Walled Carbon Nanotubes Obstruct Vesicular/Plasmalemmal Recycling in Astrocytes Down-Stream of Calcium Ions Cells doi: 10.3390/cells9071597 Authors: Manoj K Gottipati Elena Bekyarova Robert C Haddon Vladimir Parpura We used single-walled carbon nanotubes chemically functionalized with polyethylene glycol (SWCNT-PEG) to assess the effects of this nanomaterial on astrocytic endocytosis and exocytosis. We...
Wed Jul 01, 2020 03:00
Chemosensors, Vol. 8, Pages 48: Diversely Responsive Turn-On Fluorescent Cyclodextrin Chemosensors: Guest Selectivities and Mechanism Insights Chemosensors doi: 10.3390/chemosensors8030048 Authors: Hiroshi Ikeda Chemosensors have attracted considerable attention among the numerous strategies for detecting organic molecules in water. A turn-off mechanism was previously employed for the construction of a cyclodextrin (CD) chemosensor. This mechanism is greatly effective but has several...
Wed Jul 01, 2020 03:00
Children, Vol. 7, Pages 70: Drowning in Children: Retrospective Analysis of Incident Characteristics, Predicting Parameters, and Long-Term Outcome Children doi: 10.3390/children7070070 Authors: Liliane Raess Anna Darms Andreas Meyer-Heim Background: Drowning is the second leading cause of unnatural death in childhood worldwide. More than half of the drowned children, who were in need of cardiopulmonary resuscitation (CPR) at the scene suffered from lifelong neurological sequelae....
Wed Jul 01, 2020 03:00
Children, Vol. 7, Pages 69: Multi-System Inflammatory Syndrome in Children (MIS-C) Following SARS-CoV-2 Infection: Review of Clinical Presentation, Hypothetical Pathogenesis, and Proposed Management Children doi: 10.3390/children7070069 Authors: Natasha A. Nakra Dean A. Blumberg Angel Herrera-Guerra Satyan Lakshminrusimha Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection may result in the multisystem inflammatory syndrome in children (MIS-C). The clinical...
Wed Jul 01, 2020 03:00
Children, Vol. 7, Pages 68: Dexmedetomidine as an Opioid-Sparing Agent in Pediatric Craniofacial Surgery Children doi: 10.3390/children7070068 Authors: Srijaya K. Reddy Jacob J. Jones Heather Gordish-Dressman Sophie R. Pestieau Pediatric craniofacial reconstruction surgery is associated with significant perioperative analgesic requirements. As dexmedetomidine mediates central nervous system sympathetic activity and pain modulation, its intraoperative use could be beneficial...
Wed Jul 01, 2020 03:00
Cosmetics, Vol. 7, Pages 52: Effective Transcutaneous Delivery of Hyaluronic Acid Using an Easy-to-Prepare Reverse Micelle Formulation Cosmetics doi: 10.3390/cosmetics7030052 Authors: Shuto Kozaka Ayaka Kashima Rie Wakabayashi Takahiro Nakata Taro Ueda Masahiro Goto The skin loses its moisture with advancing age, causing cosmetic issues such as wrinkles. In addition, the loss of moisture leads to hypersensitivity to external stimuli such as UV light. Transcutaneous supplementation...
Wed Jul 01, 2020 03:00
Dentistry Journal, Vol. 8, Pages 63: Systematic Review on the Role of Lasers in Endodontic Therapy: Valuable Adjunct Treatment? Dentistry Journal doi: 10.3390/dj8030063 Authors: Eugenia Anagnostaki Valina Mylona Steven Parker Edward Lynch Martin Grootveld (1) Background: Adjunctive instruments, such as lasers have been investigated to address the risk of failure of endodontic therapy due to the complexity of the root canal system. Lasers have been used therapeutically, in...
Wed Jul 01, 2020 03:00
Dentistry Journal, Vol. 8, Pages 64: The Disease Process, Diagnosis and Treatment of Invasive Cervical Resorption: A Review Dentistry Journal doi: 10.3390/dj8030064 Authors: Olivia Rotondi PhiAnh Waldon Sahng G. Kim Invasive cervical resorption (ICR) is a localized, subepithelial, supra-osseous resorptive process of the tooth. Although there are several predisposing factors associated with ICR, its etiology and pathogenesis are poorly understood. The damage to the protective layer...
Wed Jul 01, 2020 03:00
Dentistry Journal, Vol. 8, Pages 66: Comparison between Shear Bond Strength of Er:YAG and Er,Cr:YSGG Lasers-Assisted Dentinal Adhesion of Self-Adhering Resin Composite: An Ex Vivo Study Dentistry Journal doi: 10.3390/dj8030066 Authors: Paul Nahas Samir Nammour Elie Gerges Toni Zeinoun (1) Background: Bonding composite to tooth structure is still evolving with a substitute for phosphoric acid being the main challenge. Lately, a self-adhering composite (SAC) was developed, promising...
Wed Jul 01, 2020 03:00
Dentistry Journal, Vol. 8, Pages 65: Efficacy of Operculectomy in the Treatment of 145 Cases with Unerupted Second Molars: A Retrospective Case–Control Study Dentistry Journal doi: 10.3390/dj8030065 Authors: Abate Cavagnetto Fama Matarese Bellincioni Assandri The aim of this study is to assess whether operculectomy in patients with retained second molars eases spontaneous tooth eruption in respect to untreated controls. Two hundred and twenty-two patients with delayed...
Wed Jul 01, 2020 03:00
Diagnostics, Vol. 10, Pages 446: Clinical and Genotypical Features of False-Negative Patients in 26 Years of Cystic Fibrosis Neonatal Screening in Tuscany, Italy Diagnostics doi: 10.3390/diagnostics10070446 Authors: Giovanni Taccetti Matteo Botti Vito Terlizzi Maria Chiara Cavicchi Anna Silvia Neri Valeria Galici Gianfranco Mergni Claudia Centrone Diego G. Peroni Filippo Festini Cystic fibrosis (CF) is a life-threatening and common genetic disorder. Cystic...
Wed Jul 01, 2020 03:00
Diagnostics, Vol. 10, Pages 445: Partial Pancreatic Parenchymal Atrophy Is a New Specific Finding to Diagnose Small Pancreatic Cancer (≤10 mm) Including Carcinoma in Situ: Comparison with Localized Benign Main Pancreatic Duct Stenosis Patients Diagnostics doi: 10.3390/diagnostics10070445 Authors: Kentaro Yamao Mamoru Takenaka Rei Ishikawa Ayana Okamoto Tomohiro Yamazaki Atsushi Nakai Shunsuke Omoto Ken Kamata Kosuke Minaga Ippei Matsumoto Yoshifumi Takeyama Isao...
Wed Jul 01, 2020 03:00
Diseases, Vol. 8, Pages 25: Reduced Skeletal Muscle Volume and Increased Skeletal Muscle Fat Deposition Characterize Diabetes in Individuals after Pancreatitis: A Magnetic Resonance Imaging Study Diseases doi: 10.3390/diseases8030025 Authors: Andre E. E. Modesto Juyeon Ko Charlotte E. E. Stuart Sakina H. H. Bharmal Jaelim Cho Maxim S. Petrov Background: Skeletal muscle has been implicated in the pathogenesis of type 2 diabetes but it has never been investigated in diabetes...
Wed Jul 01, 2020 03:00
Diversity, Vol. 12, Pages 264: Culture Collections as Hidden Sources of Microbial Biomolecules and Biodiversity Diversity doi: 10.3390/d12070264 Authors: Giudice Rizzo The application of modern advanced techniques in molecular biology is revealing unexpectedly high levels of microbial diversity and complexity. However, the invisible loss of microbial diversity in the environment deriving, for example, from global changes and anthropogenic activities, is not really perceived. In...
Wed Jul 01, 2020 03:00
Epigenomes, Vol. 4, Pages 11: Epigenetic Control in Plants Epigenomes doi: 10.3390/epigenomes4030011 Authors: Vladimir Brukhin Epigenetic regulation in plants is an exciting field of research [...]
Wed Jul 01, 2020 03:00
Fermentation, Vol. 6, Pages 66: Impact of Hanseniaspora Vineae in Alcoholic Fermentation and Ageing on Lees of High-Quality White Wine Fermentation doi: 10.3390/fermentation6030066 Authors: Del Fresno Escott Loira Herbert-Pucheta Schneider Carrau Cuerda Morata Hanseniaspora vineae is an apiculate yeast that plays a significant role at the beginning of fermentation, and it has been studied for its application in the improvement of the aromatic profile of commercial...
Wed Jul 01, 2020 03:00
Fermentation, Vol. 6, Pages 65: Effect of Candida intermedia LAMAP1790 Antimicrobial Peptides against Wine-Spoilage Yeasts Brettanomyces bruxellensis and Pichia guilliermondii Fermentation doi: 10.3390/fermentation6030065 Authors: Rubén Peña Jeniffer Vílches Camila G.-Poblete María Angélica Ganga Wine spoilage yeasts are one of the main issues in the winemaking industry, and the control of the Brettanomyces and Pichia genus is an important goal to reduce economic loses from...
Wed Jul 01, 2020 03:00
Foods, Vol. 9, Pages 863: Interaction of Monocyte-Derived Dendritic Cells with Ara h 2 from Raw and Roasted Peanuts Foods doi: 10.3390/foods9070863 Authors: Natalija Novak Soheila J. Maleki Carmen Cuadrado Jesus F. Crespo Beatriz Cabanillas Ara h 2 is a relevant peanut allergen linked to severe allergic reactions. The interaction of Ara h 2 with components of the sensitization phase of food allergy (e.g., dendritic cells) has not been investigated, and could be key to understanding...
03:00
Foods, Vol. 9, Pages 861: In Vitro Modulation of Gut Microbiota and Metabolism by Cooked Cowpea and Black Bean Foods doi: 10.3390/foods9070861 Authors: Teixeira-Guedes Sánchez-Moya Pereira-Wilson Ros-Berruezo López-Nicolás Legumes are a rich source of a wide range of compounds that may represent an important tool to overcome gut dysbiosis. In this work, the prebiotic potential of two cooked legumes (cowpea and black bean) was investigated in comparison with potato:beef...
Wed Jul 01, 2020 03:00
Δεν υπάρχουν σχόλια:
Δημοσίευση σχολίου