Publication date: Available online 30 June 2020Source: Human PathologyAuthor(s): Khaleel I. Al-Obaidy, Fatimah I. Alruwaii, Thomas M. Ulbright, Muhammad T. Idrees
Wed Jul 01, 2020 14:40
Publication date: Available online 30 June 2020Source: Human PathologyAuthor(s): Mahmut Akgul, Liang Cheng
Wed Jul 01, 2020 14:40
Nature Communications, Published online: 01 July 2020; doi:10.1038/s41467-020-17208-2Publisher Correction: Glacial–interglacial Nd isotope variability of North Atlantic Deep Water modulated by North American ice sheet
Wed Jul 01, 2020 03:00
Nature Communications, Published online: 01 July 2020; doi:10.1038/s41467-020-17104-9Severe structural deformation during (de)lithiation is the main factor limiting the stability of Si anodes in Li-ion batteries. Here, a multi-modal approach is used to visualize these deformations in their early-stage and link them to inhomogeneities in the dual-layer solid-electrolyte interphase.
Wed Jul 01, 2020 03:00
Nature Communications, Published online: 01 July 2020; doi:10.1038/s41467-020-17101-yRift Valley fever virus (RVFV) can cause severe diseases in humans, including encephalitis. Here the authors show that NSs, the major virulence factor of RVFV, is an amyloidogenic protein forming fibrils in infected mouse brains and causing increased mortality in mice.
Wed Jul 01, 2020 03:00
Nature Communications, Published online: 01 July 2020; doi:10.1038/s41467-020-17131-6High-altitude populations need special considerations for COVID-19
Wed Jul 01, 2020 03:00
Nature Communications, Published online: 01 July 2020; doi:10.1038/s41467-020-16905-2It is not clear which designs, other than completely randomized ones, are valid for scRNA-seq experiments so that batch effects can be adjusted. Here the authors show that under flexible reference panel and chain-type designs, biological variability can also be separated from batch effects, at least by BUSseq.
Wed Jul 01, 2020 03:00
Nature Communications, Published online: 01 July 2020; doi:10.1038/s41467-020-17099-3Osteocytes are mechanoresponsive within skeletal tissue. Here, the authors show that class IIa histone deacetylases are phosphorylated by focal adhesion kinase, suggesting that HDAC5 may propagate mechanobiological cues to regulate cell type-specific gene expression.
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239 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: head and neck These pubmed results were generated on 2020/07/01PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Wed Jul 01, 2020 14:38
239 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: head and neck These pubmed results were generated on 2020/07/01PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
Wed Jul 01, 2020 13:09
Related Articles Dissemination of VIM-producing Pseudomonas aeruginosa associated with high-risk clone ST654 in a tertiary and quaternary hospital in Makkah, Saudi Arabia. J Chemother. 2020 Jun 30;:1-9 Authors: Al-Zahrani IA, Al-Ahmadi BM Abstract To the best of our knowledge, no molecular surveillance that has been conducted to identify the most common clones of carbapenem-resistant Pseudomonas aeruginosa (CRPA) in western Saudi Arabia. Therefore,...
Wed Jul 01, 2020 14:37
Related Articles Association between Mixing Ability of Masticatory Functions Measured Using Color-Changing Chewing Gum and Frailty among Japanese Older Adults: The Kyoto-Kameoka Study. Int J Environ Res Public Health. 2020 Jun 24;17(12): Authors: Watanabe D, Yoshida T, Yokoyama K, Yoshinaka Y, Watanabe Y, Kikutani T, Yoshida M, Yamada Y, Kimura M, Kyoto-Kameoka Study Group Abstract The relationship between mixing ability of masticatory functions...
Wed Jul 01, 2020 14:35
Related Articles The Risk of Penetration-Aspiration Related to Residue in the Pharynx. Am J Speech Lang Pathol. 2020 Jun 29;:1-10 Authors: Steele CM, Peladeau-Pigeon M, Barrett E, Wolkin TS Abstract Purpose Reference data from healthy adults under the age of 60 years suggest that the 75th and 95th percentiles for pharyngeal residue on swallows of thin liquids are 1% and 3%(C2-4)2, respectively. We explored how pharyngeal residue below versus...
Wed Jul 01, 2020 14:35
Related Articles Retrograde fiberoptic endoscopy evaluation for patients with laryngeal edema. Laryngoscope Investig Otolaryngol. 2020 Jun;5(3):473-476 Authors: Alfaris AM, Bawazir SM, Al Awaji NN Abstract Background: Airway and swallowing evaluation is a crucial step before weaning the patient from a tracheostomy tube. Different evaluation procedures can be used successfully in many patients, but sometimes, this can be difficult or impossible...
Wed Jul 01, 2020 14:35
Related Articles Differentiation of Feeding Behaviors Based on Masseter and Supra-Hyoid Muscle Activity. Front Physiol. 2020;11:618 Authors: Uehara F, Hori K, Murakami K, Okawa J, Ono T Abstract Older adults with disorders of mastication and swallowing are often fed soft foods such as jelly or puree. The texture of such semi-solid foods allows them to be squeezed between the tongue and palate rather than being chewed. However, it is difficult...
Wed Jul 01, 2020 14:35
Related Articles Screening dysphagia risk in 534 older patients undergoing rehabilitation after total joint replacement. A cross-sectional study. Eur J Phys Rehabil Med. 2020 Jun 26;: Authors: de Sire A, Giachero A, De Santi S, Inglese K, Solaro C Abstract BACKGROUND: Older people affected by severe osteoarthritis could need to undergo total joint replacement, with a consequent hospitalization and rehabilitation. In this post-acute phase, they...
Wed Jul 01, 2020 14:35
Related Articles NASQAR: a web-based platform for high-throughput sequencing data analysis and visualization. BMC Bioinformatics. 2020 Jun 29;21(1):267 Authors: Yousif A, Drou N, Rowe J, Khalfan M, Gunsalus KC Abstract BACKGROUND: As high-throughput sequencing applications continue to evolve, the rapid growth in quantity and variety of sequence-based data calls for the development of new software libraries and tools for data analysis and visualization....
Wed Jul 01, 2020 14:33
Related Articles Methylation data imputation performances under different representations and missingness patterns. BMC Bioinformatics. 2020 Jun 29;21(1):268 Authors: Lena PD, Sala C, Prodi A, Nardini C Abstract BACKGROUND: High-throughput technologies enable the cost-effective collection and analysis of DNA methylation data throughout the human genome. This naturally entails missing values management that can complicate the analysis of the...
Wed Jul 01, 2020 14:33
Related Articles Robust principal component analysis for accurate outlier sample detection in RNA-Seq data. BMC Bioinformatics. 2020 Jun 29;21(1):269 Authors: Chen X, Zhang B, Wang T, Bonni A, Zhao G Abstract BACKGROUND: High throughput RNA sequencing is a powerful approach to study gene expression. Due to the complex multiple-steps protocols in data acquisition, extreme deviation of a sample from samples of the same treatment group may occur...
Wed Jul 01, 2020 14:33
Related Articles Cost benefit of coblation versus electrocautery adenotonsillectomy for pediatric patients. Int J Pediatr Otorhinolaryngol. 2020 Jun 20;136:110197 Authors: McCoy JL, Maguire RC, Tobey ABJ Abstract INTRODUCTION: Coblation and electrocautery are two common techniques used for adenotonsillectomy (T&A). Numerous studies have assessed surgical outcomes of coblation versus electrocautery and overall, postoperative complications...
Wed Jul 01, 2020 14:30
Related Articles MiRNA-145-5p prevents differentiation of oligodendrocyte progenitor cells by regulating expression of myelin gene regulatory factor. J Cell Physiol. 2020 Jun 30;: Authors: Kornfeld SF, Cummings SE, Fathi S, Bonin SR, Kothary R Abstract The roles of specific microRNAs (miRNA) in oligodendrocyte (OL) differentiation have been studied in depth. However, miRNAs in OL precursors and oligodendrocyte progenitor cells (OPCs) have been...
Wed Jul 01, 2020 14:26
Related Articles Expression of ApoA5 and its function in the right ventricular failing and remodeling secondary to pulmonary hypertension. J Cell Physiol. 2020 Jun 30;: Authors: Chen J, Luo J, Yang X, Ouyang M, Zhu T, Li Y, Luo P, Chen Y, Li Z, Li J Abstract Right heart failure and right ventricular (RV) remodeling were the main reason for mortality of pulmonary hypertension (PH) patients. Apolipoprotein AV (ApoA5) is a key regulator of plasma...
Wed Jul 01, 2020 14:26
Related Articles MicroRNA alterations in neuropathologic cognitive disorders with an emphasis on dementia: Lessons from animal models. J Cell Physiol. 2020 Jun 30;: Authors: Bahlakeh G, Gorji A, Soltani H, Ghadiri T Abstract Cognitive dysfunction is a state of losing or having difficulties in remembering, learning, focusing, or making decisions that impact individual healthy life. Small single-stranded and nonprotein coding RNAs, microRNAs (miRNAs)...
Wed Jul 01, 2020 14:26
Abstract Introduction Improvements of surgical visualization add value to the quality of clinical routine and offer the opportunity to improve surgical education of medical staff. The aim of this study was to determine whether otorhinolaryngology trainees gain additional comprehension of the anatomical structures and the surgical site when 3D visualization is used. Methods ...
Wed Jul 01, 2020 03:00
Related Articles Disparities in Access to Healthy Diets: How Food Security and Food Shopping Behaviors Relate to Fruit and Vegetable Intake. J Acad Nutr Diet. 2020 Jun 24;: Authors: Drisdelle C, Kestens Y, Hamelin AM, Mercille G Abstract BACKGROUND: Food shopping behaviors may help determine how local food environments influence fruit and vegetable (F/V) intake, especially among food insecure households. OBJECTIVE: To examine whether...
Wed Jul 01, 2020 14:23
Related Articles The Pediatric Subjective Global Nutrition Assessment Classifies More Children With Cerebral Palsy as Malnourished Compared With Anthropometry. J Acad Nutr Diet. 2020 Jun 24;: Authors: Bell KL, Benfer KA, Ware RS, Patrao TA, Garvey JJ, Haddow R, Boyd RN, Davies PSW, Arvedson JC, Weir KA Abstract BACKGROUND: Nutrition assessment is multidimensional; however, much of the literature examining the nutritional status of children with...
Wed Jul 01, 2020 14:23
Related Articles Corrigendum. J Acad Nutr Diet. 2020 Jun 24;: Authors: PMID: 32593666 [PubMed - as supplied by publisher]
Wed Jul 01, 2020 14:23
Related Articles Nanomedicine in Thrombosis and Hemostasis: The Future of Nanotechnology in Thrombosis and Hemostasis Research and Clinical Applications. Semin Thromb Hemost. 2020 Jul;46(5):521-523 Authors: Hagemeyer CE, Lisman T, Kwaan HC PMID: 32604418 [PubMed - as supplied by publisher]
Wed Jul 01, 2020 14:19
Related Articles The PARP inhibitor, olaparib, depletes the ovarian reserve in mice: implications for fertility preservation. Hum Reprod. 2020 Jun 30;: Authors: Winship AL, Griffiths M, Lliberos Requesens C, Sarma U, Phillips KA, Hutt KJ Abstract STUDY QUESTION: What is the impact of the poly(ADP-ribose) polymerase (PARP) inhibitor, olaparib, alone or in combination with chemotherapy on the ovary in mice? SUMMARY ANSWER: Olaparib treatment,...
Wed Jul 01, 2020 14:19
Related Articles A Fragile Balance: The Important Role of the Intestinal Microbiota in the Prevention and Management of Colorectal Cancer. Oncology. 2020 Jun 30;:1-10 Authors: Toumazi D, Constantinou C Abstract BACKGROUND: Colorectal cancer is the second leading cause of cancer-related death worldwide. In recent years, researchers have focussed on the role of the intestinal microbiota in both the prevention and the treatment of colorectal cancer....
Wed Jul 01, 2020 14:19
Related Articles Emerging Role of Elastin-Like Polypeptides (ELPs) in Regenerative Medicine. Adv Wound Care (New Rochelle). 2020 Jun 30;: Authors: Sarangthem V, Singh TD, Dinda AK Abstract SIGNIFICANCE: Wound dressing based on naturally derived polymer provides a useful platform for the treatment of skin injuries. Owing to the high mechanical strength, tunable structural and physicochemical properties of human elastin-like polypeptides (ELPs),...
Wed Jul 01, 2020 14:19
Related Articles Impact of COVID-19 Pandemic on Oncology Practices During Nationwide Lockdown Period: A Single Centre Experience and the Way Forward. J Assoc Physicians India. 2020 Jul;68(7):48-50 Authors: Sundriyal D, Sehrawat A, Kumar P, Bhandari R Abstract Background: The COVID-19 pandemic has posed a grave challenge to mankind as it doesn't appear to get controlled in the near future. Worldwide, health care centers are working more than...
Wed Jul 01, 2020 14:19
Related Articles Systematic Review of the Kynurenine Pathway and Psychoneurological Symptoms Among Adult Cancer Survivors. Biol Res Nurs. 2020 Jun 30;:1099800420938141 Authors: Li H, Liu T, Heinsberg LW, Lockwood MB, Wainwright DA, Jang MK, Doorenbos AZ Abstract The co-occurrence of multiple psychoneurological symptoms, including pain, sleep disturbance, fatigue, depression, anxiety, and cognitive disturbance among adult cancer survivors led...
Wed Jul 01, 2020 14:19
Related Articles Efficacy and safety of a new rifabutin-based triple therapy with vonoprazan for refractory Helicobacter pylori infection: A prospective single-arm study. Helicobacter. 2020 Jun 29;:e12719 Authors: Hirata Y, Yamada A, Niikura R, Shichijo S, Hayakawa Y, Koike K Abstract BACKGROUND: A small proportion of Helicobacter pylori-infected individuals in Japan suffer failure of eradication therapy with third-line regimens containing the...
Wed Jul 01, 2020 14:19
Related Articles An Update on Surgical Margins in the Head Neck Squamous Cell Carcinoma: Assessment, Clinical Outcome, and Future Directions. Curr Oncol Rep. 2020 Jun 30;22(8):82 Authors: Singh A, Qayyumi B, Chaturvedi P Abstract PURPOSE OF REVIEW: Failure to achieve tumor-free margins is the single largest cause of death for head neck cancer patients. At the same time, it is the only factor that is in complete control of the surgeon. This review...
Wed Jul 01, 2020 14:19
Related Articles MAP-Kinase-Driven Hematopoietic Neoplasms: A Decade of Progress in the Molecular Age. Cold Spring Harb Perspect Med. 2020 Jun 29;: Authors: Chakraborty R, Abdel-Wahab O, Durham BH Abstract Mutations in members of the mitogen-activated protein kinase (MAPK) pathway are extensively studied in epithelial malignancies, with BRAF mutations being one of the most common alterations activating this pathway. However, BRAF mutations are...
Wed Jul 01, 2020 14:19
Related Articles Tim-3 finds its place in the cancer immunotherapy landscape. J Immunother Cancer. 2020 Jun;8(1): Authors: Acharya N, Sabatos-Peyton C, Anderson AC Abstract The blockade of immune checkpoint receptors has made great strides in the treatment of major cancers, including melanoma, Hodgkin's lymphoma, renal, and lung cancer. However, the success rate of immune checkpoint blockade is still low and some cancers, such as microsatellite-stable...
Wed Jul 01, 2020 14:19
Related Articles Management of older and frail patients with multiple Myeloma in the Portuguese routine clinical practice: Deliberations and recommendations from an expert panel of hematologists. J Geriatr Oncol. 2020 Jun 26;: Authors: João C, Geraldes C, Neves M, Mariz M, Trigo F Abstract The management of older patients with Multiple Myeloma (MM) is particularly challenging due to the highly heterogeneous nature of this population, both in...
Wed Jul 01, 2020 14:19
Related Articles Functional recovery in older women undergoing surgery for gynaecological malignancies: A systematic review and narrative synthesis. J Geriatr Oncol. 2020 Jun 27;: Authors: Martin FE, Kalsi T, Baker H, Bharathan R, Sbai M, Partridge JSL, Dhesi JK Abstract OBJECTIVES: Older women are increasingly undergoing surgery for gynaecological malignancies. Although survival data is available other outcomes such as functional recovery are...
Wed Jul 01, 2020 14:19
Related Articles Lapatinib plus Capecitabine versus Trastuzumab plus Capecitabine in the Treatment of Human Epidermal Growth Factor Receptor 2-positive Metastatic Breast Cancer with Central Nervous System Metastases for Patients Currently or Previously Treated with Trastuzumab (LANTERN): a Phase II Randomised Trial. Clin Oncol (R Coll Radiol). 2020 Jun 26;: Authors: Seligmann JF, Wright-Hughes A, Pottinger A, Velikova G, Oughton JB, Murden G, Rizwanullah M, Price...
Wed Jul 01, 2020 14:19
Related Articles Features of Mild-to-Moderate COVID-19 Patients With Dysphonia. J Voice. 2020 Jun 04;: Authors: Lechien JR, Chiesa-Estomba CM, Cabaraux P, Mat Q, Huet K, Harmegnies B, Horoi M, Bon SDL, Rodriguez A, Dequanter D, Hans S, Crevier-Buchman L, Hochet B, Distinguin L, Chekkoury-Idrissi Y, Circiu M, El Afia F, Barillari MR, Cammaroto G, Fakhry N, Michel J, Radulesco T, Martiny D, Lavigne P, Jouffe L, Descamps G, Journe F, Trecca EMC, Hsieh J, Delgado...
Wed Jul 01, 2020 14:19
Related Articles Development of pharmaceutically scalable inhaled anti-cancer nanotherapy - Repurposing amodiaquine for non-small cell lung cancer (NSCLC). Mater Sci Eng C Mater Biol Appl. 2020 Oct;115:111139 Authors: Parvathaneni V, Kulkarni NS, Chauhan G, Shukla SK, Elbatanony R, Patel B, Kunda NK, Muth A, Gupta V Abstract New drug and dosage form development faces significant challenges, especially in oncology, due to longer development cycle...
Wed Jul 01, 2020 14:19
Related Articles Radiation Therapy for Patients with Advanced Renal Cell Carcinoma. Urol Clin North Am. 2020 Aug;47(3):399-411 Authors: Miccio JA, Oladeru OT, Jun Ma S, Johung KL Abstract Stereotactic radiosurgery and stereotactic body radiation therapy (SBRT) have led to a resurgence of the use of radiotherapy in the management of advanced renal cell carcinoma (RCC). These techniques provide excellent local control and palliation of metastatic...
Wed Jul 01, 2020 14:19
Related Articles Common signal transduction molecules activated by bacterial entry into a host cell and by reactive oxygen species. Antioxid Redox Signal. 2020 Jun 29;: Authors: Bonavita R, Laukkanen MO Abstract SIGNIFICANCE: An increasing number of pathogens are acquiring resistance to antibiotics. Efficient antimicrobial drug regimens are important even for the most advanced therapies, which range from cutting-edge invasive clinical protocols,...
Wed Jul 01, 2020 14:19
Related Articles Measuring Goal-Concordant Care: Results and reflections from secondary analysis of a trial to improve serious illness communication. J Pain Symptom Manage. 2020 Jun 26;: Authors: Sanders JJ, Miller K, Desai M, Geerse OP, Paladino J, Kavanagh J, Lakin JR, Neville BA, Block SD, Fromme EK, Bernacki R Abstract CONTEXT: Many consider goal-concordant care (GCC) to be the most important of advance care planning and palliative care....
Wed Jul 01, 2020 14:19
Related Articles [Epidemiology of multiple myeloma in city Moscow]. Ter Arkh. 2019 Jul 15;91(7):83-92 Authors: Vinogradova OY, Ptushkin VV, Chernikov MV, Kochkareva YB, Zherebtsova VA Abstract AIM: To study the epidemiology of multiple myeloma in the city of Moscow and compare the results obtained with data from similar studies in other countries. MATERIALS AND METHODS: The study is based on information from a database of case histories...
Wed Jul 01, 2020 14:19
Related Articles Real-world effectiveness of nivolumab in patients with non-small-cell lung cancer: a systematic review and meta-analysis. Future Oncol. 2020 Jun 29;: Authors: Kim YJ, Oremus M, Chen HH, McFarlane T, Shah D, Horton S Abstract Background: The effectiveness of immunotherapies for non-small-cell lung cancer under real-world clinical settings remains uncertain. Materials & methods: Systematic searches of PubMed, EMBASE and Web...
Wed Jul 01, 2020 14:19
Related Articles Clinico-radiological monitoring strategies in patients with metastatic breast cancer: a real-world study. Future Oncol. 2020 Jun 29;: Authors: Bonotto M, Basile D, Gerratana L, Bartoletti M, Lisanti C, Pelizzari G, Vitale MG, Fanotto V, Poletto E, Minisini AM, Russo S, Andreetta C, Mansutti M, Fasola G, Puglisi F Abstract Aim: A monitoring strategy for metastatic breast cancer patients (M-MBC) has been little studied. Materials...
Wed Jul 01, 2020 14:19
Related Articles Rituximab biosimilars in hematologic malignancies: the need for a real-world approach. Future Oncol. 2020 Jun 29;: Authors: Nava-Parada P, Shelbaya A, Nabhan C Abstract The introduction of rituximab biosimilars into healthcare systems can potentially help to control healthcare costs for the treatment of hematologic malignancies. However, there are currently several barriers to the uptake of biosimilars. This review discusses...
Wed Jul 01, 2020 14:19
Related Articles Association between single nucleotide polymorphisms of DNA damage response pathway genes and increased risk in breast cancer. Future Oncol. 2020 Jun 27;: Authors: Mehmood A, Kayani MA, Ahmed MW, Nisar A, Mahjabeen I Abstract Aim: We aimed to evaluate the role of selected single nucleotide polymorphisms of DNA damage response pathway genes in breast cancer (BC). Materials & methods: In present study, 500 BC patients and 500...
Wed Jul 01, 2020 14:19
Related Articles Implications of COVID-19 on urological laparoscopic surgery. Future Oncol. 2020 Jun 27;: Authors: Condon B, Whish-Wilson T, Davis NF, Lawrentschuk N PMID: 32597203 [PubMed - as supplied by publisher]
Wed Jul 01, 2020 14:19
Related Articles Living with long-term consequences: experience of follow-up care and support needs among Asian long-term colorectal cancer survivors. Psychooncology. 2020 Jun 28;: Authors: Yoon S, Chua TB, Tan IB, Matchar D, Ong MEH, Tan E Abstract OBJECTIVES: This study aimed to provide an in-depth exploration of follow-up care experiences and supportive care needs in long-term colorectal cancer (CRC) survivors within multiethnic Asian communities....
Wed Jul 01, 2020 14:19
Related Articles Age, pathology and CA-125 are prognostic factors for survival in patients with brain metastases from gynaecological tumours. Clin Transl Radiat Oncol. 2020 Sep;24:11-15 Authors: Nagtegaal SHJ, Hulsbergen AFC, van Dorst EBL, Kavouridis VK, Jessurun CAC, Broekman MLD, Smith TR, Verhoeff JJC Abstract Background and purpose: Brain metastases originating from gynaecological tumours are a rare phenomenon, but have an increasing incidence...
Wed Jul 01, 2020 14:19
Related Articles Quality of Life, Toxicity and Unmet Needs in Nasopharyngeal Cancer Survivors. Front Oncol. 2020;10:930 Authors: McDowell L, Corry J, Ringash J, Rischin D Abstract Concerted research efforts over the last three decades have resulted in improved survival and outcomes for patients diagnosed with nasopharyngeal carcinoma (NPC). The evolution of radiotherapy techniques has facilitated improved dose delivery to target volumes while...
Wed Jul 01, 2020 14:19
Related Articles Integrating Loco-Regional Hyperthermia Into the Current Oncology Practice: SWOT and TOWS Analyses. Front Oncol. 2020;10:819 Authors: Datta NR, Kok HP, Crezee H, Gaipl US, Bodis S Abstract Moderate hyperthermia at temperatures between 40 and 44°C is a multifaceted therapeutic modality. It is a potent radiosensitizer, interacts favorably with a host of chemotherapeutic agents, and, in combination with radiotherapy, enforces immunomodulation...
Wed Jul 01, 2020 14:19
Related Articles Effects of exercise therapy in cancer patients undergoing radiotherapy treatment: a narrative review. SAGE Open Med. 2020;8:2050312120922657 Authors: Piraux E, Caty G, Aboubakar Nana F, Reychler G Abstract Despite its beneficial effects, radiotherapy still results in a range of side effects that negatively impact quality of life of patients. Exercise has been shown to counteract the side effects induced by cancer treatment....
Wed Jul 01, 2020 14:19
Related Articles Surrogate endpoints for overall survival in anti-programmed death-1 and anti-programmed death ligand 1 trials of advanced melanoma. Ther Adv Med Oncol. 2020;12:1758835920929583 Authors: Nie RC, Yuan SQ, Wang Y, Zou XB, Chen S, Li SM, Duan JL, Zhou J, Chen GM, Luo TQ, Zhou ZW, Li YF Abstract Background: We assessed the surrogacy of objective response rate (ORR), disease control rate (DCR) and progression-free survival (PFS)...
Wed Jul 01, 2020 14:19
Related Articles Obesity and Cancer Treatment Outcomes: Interpreting the Complex Evidence. Clin Oncol (R Coll Radiol). 2020 Jun 25;: Authors: Slawinski CGV, Barriuso J, Guo H, Renehan AG Abstract A wealth of epidemiological evidence, combined with plausible biological mechanisms, present a convincing argument for a causal relationship between excess adiposity, commonly approximated as body mass index (BMI, kg/m2), and incident cancer risk. Beyond...
Wed Jul 01, 2020 14:19
Related Articles Molecular Imaging for Particle Therapy: Current Approach and Future Directions. Recent Results Cancer Res. 2020;216:865-879 Authors: Seidensaal K, Harrabi SB, Debus J Abstract During the last decades, radiation oncology has been subject to a number of technological innovations. Particle therapy has evolved in parallel to the modern high-precision photon radiotherapy techniques and offers a superior dose distribution with decreased...
Wed Jul 01, 2020 14:19
Related Articles Next-generation CAR T cells to overcome current drawbacks. Int J Hematol. 2020 Jun 27;: Authors: Lundh S, Maji S, Melenhorst JJ Abstract As a rapidly emerging treatment in the oncology field, adoptive transfer of autologous, genetically modified chimeric antigen receptor (CAR) T cells has shown striking efficacy and is curative in certain relapsed/refractory patients with hematologic malignancy. This treatment modality of using...
Wed Jul 01, 2020 14:19
Related Articles Mapping the Current State of Canadian Medical School Oncology Interest Groups. J Cancer Educ. 2020 Jun 27;: Authors: Malik NH, Li GJ, Giuliani M, Brundage M, Caissie A, Cao JQ, Halperin R, Ingledew PA, Vigneault E, Bezjak A Abstract Cancer is the leading cause of mortality in Canada. Undergraduate medical education therefore must ensure adequate oncology education for all physicians and inspire some to make oncology their career...
Wed Jul 01, 2020 14:19
Related Articles Installing oncofertility programs for common cancers in limited resource settings (Repro-Can-OPEN Study): An extrapolation during the global crisis of Coronavirus (COVID-19) pandemic. J Assist Reprod Genet. 2020 Jun 27;: Authors: Salama M, Ataman-Millhouse L, Braham M, Berjeb K, Khrouf M, Rodrigues JK, Reis FM, Silva TC, Sánchez F, Romero S, Smitz J, Vásquez L, Vega M, Sobral F, Terrado G, Lombardi MG, Scarella A, Bourlon MT, Verduzco-Aguirre...
Wed Jul 01, 2020 14:19
Related Articles Exploring DNA Methylation for Prognosis and Analyzing the Tumor Microenvironment in Pleomorphic Xanthoastrocytoma. J Neuropathol Exp Neurol. 2020 Jun 28;: Authors: Tang K, Kurland D, Vasudevaraja V, Serrano J, Delorenzo M, Radmanesh A, Thomas C, Spino M, Gardner S, Allen JC, Nicolaides T, Osorio DS, Finlay JL, Boué DR, Snuderl M Abstract Pleomorphic xanthoastrocytoma (PXA) is a rare type of brain tumor that affects children...
Wed Jul 01, 2020 14:19
Related Articles Recent advancements in liposome technology. Adv Drug Deliv Rev. 2020 Jun 25;: Authors: Filipczak N, Pan J, Yalamarty SSK, Torchilin VP Abstract The liposomes have continued to be well-recognized as an important nano-sized drug delivery system with attractive properties, such a characteristic bilayer structure assembling the cellular membrane, easy-to-prepare and high bio-compatibility. Extensive effort has been devoted to the...
Wed Jul 01, 2020 14:19
Related Articles Management of Nonpregnant Women Presenting to the Emergency Department With Iron Deficiency Anemia Caused by Uterine Blood Loss: A Retrospective Cohort Study. J Emerg Med. 2020 Jun 24;: Authors: Boone S, Peacock WF, Ordonez E, Powers JM Abstract BACKGROUND: Women with abnormal uterine bleeding are commonly encountered in the emergency department (ED). Contemporary management of severe iron deficiency anemia (IDA) in this setting...
Wed Jul 01, 2020 14:19
Related Articles Review of embryo-fetal developmental toxicity studies performed for pharmaceuticals approved by FDA in 2018 and 2019. Reprod Toxicol. 2020 Jun 25;: Authors: Barrow P, Clemann N Abstract Details of embryo-fetal development (EFD) studies were compiled for all FDA drug approvals in 2018-19. EFD studies were performed for 82% of approvals (84% of small molecules and 70% of biopharmaceuticals). Rats and rabbits were used for 84%...
Wed Jul 01, 2020 14:19
Related Articles Modified Apical Dissection and Lateral Prostatic Fascia Preservation Improves Early Postoperative Functional Recovery in Robotic-assisted Laparoscopic Radical Prostatectomy: Results from a Propensity Score-matched Analysis. Eur Urol. 2020 Jun 24;: Authors: Covas Moschovas M, Bhat S, Onol FF, Rogers T, Roof S, Mazzone E, Mottrie A, Patel V Abstract BACKGROUND: Early recovery of continence and potency after robotic-assisted laparoscopic...
Wed Jul 01, 2020 14:19
Related Articles MET receptor in oncology: From biomarker to therapeutic target. Adv Cancer Res. 2020;147:259-301 Authors: Malik R, Mambetsariev I, Fricke J, Chawla N, Nam A, Pharaon R, Salgia R Abstract First discovered in the 1984, the MET receptor tyrosine kinase (RTK) and its ligand hepatocyte growth factor or HGF (also known as scatter factor or SF) are implicated as key players in tumor cell migration, proliferation, and invasion in a...
Wed Jul 01, 2020 14:19
Related Articles Optimizing childhood oncology care transition from pediatric to adult settings: A survey of primary care physicians' and residents' perspectives. Clin Invest Med. 2020 Jun 28;43(2):E14-23 Authors: Marcoux SMMP, Laverdière C Abstract PURPOSE: The majority of childhood cancer survivors suffer from late adverse effects after the completion of treatment. The prospect of most survivors reaching middle-age is a relatively new phenomenon,...
Wed Jul 01, 2020 14:19
Related Articles 89Zr-Immuno-PET: Toward a Noninvasive Clinical Tool to Measure Target Engagement of Therapeutic Antibodies In Vivo. J Nucl Med. 2019 12;60(12):1825-1832 Authors: Jauw YWS, O'Donoghue JA, Zijlstra JM, Hoekstra OS, Menke-van der Houven van Oordt CW, Morschhauser F, Carrasquillo JA, Zweegman S, Pandit-Taskar N, Lammertsma AA, van Dongen GAMS, Boellaard R, Weber WA, Huisman MC Abstract 89Zr-immuno-PET is a promising noninvasive...
Wed Jul 01, 2020 14:19
Related Articles Twenty-five-Year Follow-up of Short-term Cancer Research Trainees at the University of Alabama at Birmingham: a Brief Report. J Cancer Educ. 2019 Oct;34(5):1010-1013 Authors: Desmond RA, Venkatesh R, Padilla LA, Daniel CL, Litton AG, Heimburger DC, Michael Brooks C, Waterbor JW Abstract Long-term follow-up is needed to evaluate the impact of short-term cancer research programs on the career trajectories of medical and graduate...
Wed Jul 01, 2020 14:19
Abstract The distribution of resources is a crucial determinant of animals' space use (e.g., daily travel distance, monthly home range size, and revisitation patterns). We examined how variation in ecological parameters affected variability in space use patterns of western lowland gorillas, Gorilla gorilla gorilla . They are an interesting species for investigating this topic because key components of their diet are nonfruit items (herbaceous vegetation and tree leaves) that occur at low density...
Tue Jun 30, 2020 21:56
Abstract Population size and distribution data for wildlife species play an important role in conservation and management, especially for endangered species. However, scientists seriously lack data on the population status of many species. The northern yellow‐cheeked gibbon (Nomascus annamensis ) is found in southern Lao PDR, central Vietnam, and northeastern Cambodia. The population of the species has significantly declined due to hunting, habitat loss, and the wildlife trade. To examine...
Tue Jun 30, 2020 21:55
Adult male black howler monkey in secondary growth at the edge of a forest fragment. Abstract For wild primates, demography studies are increasingly recognized as necessary for assessing the viability of vulnerable populations experiencing rapid environmental change. In particular, anthropogenic changes such as habitat loss and fragmentation can cause ecological and behavioral changes in small, isolated populations, which may, over time, alter population density and demographic structure (age/sex...
Tue Jun 30, 2020 11:02
The percentage of time the Da Gama and Slangkop troops spent in urban (grey) and non‐urban (white) areas when monitors were present and absent. Abstract The transformation of natural land for agricultural and urban use has displaced baboons from large parts of their historical distribution. Abundant resources within transformed areas, however, continue to attract baboons back into these human‐dominated areas resulting in chronic levels of conflict throughout much of Africa. In the city of Cape...
Tue Jun 30, 2020 11:01
Publication date: Available online 1 July 2020Source: Annals of Diagnostic PathologyAuthor(s): Nuno Jorge Lamas, Sara Esteves, Joana Raposo Alves, Francisca Emanuel Costa, David Tente, Paula Fonseca, José Ramón Vizcaíno
Wed Jul 01, 2020 14:42
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