Wed Jul 01, 2020 12:24
Abstract Although there are few randomized controlled trials (RCTs) evaluating the efficacy of drugs to treat COVID‐19, different molecules have been used empirically and with great interest in those intended to control the excessive inflammatory response produced by SARS‐CoV‐2. By blocking the IL‐6 receptor, tocilizumab has a role in controlling the inflammatory response. Clinical improvement of respiratory parameters and hospital stay have been described in small series in a series of patients...
Tue Jun 30, 2020 19:14
Abstract Background Atrophic scars that occur after surgical procedure or trauma are considered as a cosmetic problem for patients. Atrophic scarring results usually during wound healing with inadequate production of collagen and connective tissue. Factors that precipitate to the formation of depressed scars include: individual variations in wound healing, wound tension, tissue apposition, and scar contraction. Objectives To evaluate the safety and efficacy of PRP versus carboxytherapy...
Tue Jun 30, 2020 16:53
Abstract The 755 nm picosecond Alexandrite laser has been demonstrated to be effective and well tolerated in patients with acne scars. In this split‐face, investigator‐blinded study, 16 patients with post‐inflammatory erythema (PIE) and acne scars were randomized to receive laser treatment on half the face, with the other half serving as a control. The treatment side demonstrated a significant improvement in both PIE and scars compared to the baseline and also when compared to the control side....
Tue Jun 30, 2020 16:49
Tue Jun 30, 2020 16:30
Tue Jun 30, 2020 16:30
Abstract Ma'aljobon, a handmade substance, is the liquid portion of coagulated milk after adding vinegar to the heated milk. In traditional Persian medicine (TPM) it has been known as a useful remedy for the treatment of some skin disorders. The aim of this study was to review the applications of Ma'aljobon for skin diseases according to the sages of TPM and modern medicine. Main TPM sources were reviewed with the keyword of “Ma'aljobon ”. Furthermore, electronic databases including Scopus, PubMed,...
Tue Jun 30, 2020 12:35
Abstract Ingenol Mebutate (IM), as an active compound is derived from the sap of the Euphorbia peplus , which is an FDA ‐approved plant for the treatment of actinic keratosis. Some reports have demonstrated that the IM gel 0.05% is safe and effective in the treatment of external anogenital warts but the efficacy of the drug on the recalcitrant anogenital warts is not clear. to assess the efficacy and safety of the IM gel 0.05% for cryotherapy ‐resistant anogenital warts. Totally, 15 cryotherapy‐resistant...
Tue Jun 30, 2020 12:07
Tue Jun 30, 2020 11:45
Tue Jun 30, 2020 11:32
Abstract Rapid diagnosis of pemphigus vulgaris (PV) is an important task in patient's prognosis and treatment. Although PV is routinely diagnosed through investigation of pathology specimens and direct immunofluorescence assays, Tzanck smear can be used as rapid, inexpensive and easily used test to confirm its clinical diagnosis. This study aimed to determine the diagnostic value of Tzanck smear in erosive oral lesions of PV and determination of its sensitivity and specificity for diagnostic purposes....
Tue Jun 30, 2020 11:15
AbstractProbing the neural mechanisms that underlie each sensory system requires the presentation of perceptually appropriate stimulus concentrations. This is particularly relevant in the olfactory system as additional odorant receptors typically respond with increasing stimulus concentrations. Thus, perceptual measures of olfactory sensitivity provide an important guide for functional experiments. This study focuses on aliphatic alcohols because they are commonly used to survey neural activity in...
Wed Jul 01, 2020 03:00
Since January 2020, the spread of the COVID-19 pandemic in China and, in the next weeks, in Italy and then in the rest of Europe and the world, has had an enormous impact on the organization, safety procedures and prescription behavior of the physicians in radiation oncology. The main concerns expressed in the numerous comments, letters and papers published in the last three months are a) how to assure the normal supply of the radiotherapy treatments; b) how to keep constant the number of Healthcare...
Wed Jul 01, 2020 03:00
The prevalence of chronic wrist pain and subsequent functional decline is increasing. Diagnosis is challenging, with non-surgical treatment frequently failing. Recently, partial wrist denervation (PWD) has gained popularity as a procedure to alleviate chronic pain.
Wed Jul 01, 2020 03:00
Abstract Background To investigate the practice regarding breast MRI exams and breast MRI-guided biopsies in two countries with different health care systems, France and Québec. A 12-item questionnaire was distributed online among radiologists from France and Québec, attempting to determine: demographic characteristics and breast MRI diagnostic and MRI-guided practices (indications, workload, availability, and waiting time assessment)....
Wed Jul 01, 2020 03:00
Peanut allergy affects approximately 2% of children in the United States1. Delayed introduction of allergenic foods was recommended by the AAP in 2000 in an effort to reduce incidence of allergic disease.2 This recommendation was withdrawn in 2008 due to insufficient evidence and no specific guidance was provided on the timing of allergenic food introduction.3 In January 2017, evidence-based recommendations for the early introduction of peanut
Wed Jul 01, 2020 03:00
Condylar hyperplasia is known to result in facial asymmetries and constitutes a well-recognized group of unilateral mandibular enlargements. Condylar hyperplasia has been sub-classified into hemimandibular hyperplasia and hemimandibular elongation. A much rarer disorder, hemifacial hyperplasia (or hemifacial hypertrophy) is a congenital malformation characterized by prominent unilateral overdevelopment of the hard and soft tissues of the face. The affected side grows at a faster rate than the non-affected...
Wed Jul 01, 2020 03:00
Varian Medical Systems, based in Palo Alto, California, has announced that its Noona mobile service now has some new features, some of which are a direct response to the COVID-19 pandemic. Noona is a cloud-based system that allows cancer patients to connect with their clinicians and clinics. Patients can record their symptoms and proactively manage their conditions. The idea is that issues can be flagged early and the resulting preemptive action could enhance patient outcomes. In...
Wed Jul 01, 2020 23:50
Boston Scientific has announced winning FDA clearance for its LUX-Dx Insertable Cardiac Monitor (ICM), an implant that can detect hard-to-spot cardiac arrhythmias, such as atrial fibrillation, and help diagnose their origin. The device’s detection algorithm has two separate components, one of which detects a suspect arrhythmia and the other verifies the finding. Once an arrhythmia is confirmed, the wireless device sends a signal to the patient’s cardiologist via an app installed on...
Wed Jul 01, 2020 18:52
In this prospective study we evaluated the duration of insertion and the accuracy of fitting of computer-aided design (CAD)-based pre-bent orbital floor plates compared with non-preformed orbital plates in reconstruction of the orbital floor. Thirty-six patients with unilateral fractures of the orbital floor were included; pre-bent plates were used in 25 and non-preformed plates in 11. Preoperative computed tomography (CT) scans were used for CAD of individualised implants. The anatomy of the affected...
Wed Jul 01, 2020 03:00
We read with pleasure the article written by Mohamed et al1 about biphasic external fixation of mandibular fractures. This article described how to technically perform an external fixation device using a biphasic system inspired after the one created by Morris.2 We agree with the authors that external fixation now has limited indications, but is still a very interesting option in selected cases, such as pathological fractures due to osteoradionecrosis or infection.3
Wed Jul 01, 2020 03:00
Donor site complications, following microvascular free tissue transfer, can limit recovery in patients treated for head and neck cancer, with a curative intent. The Patient Concerns Inventory (PCI-HN) is a prompt list that provides patients with repeated opportunities to raise issues they feel are important and want to discuss. Here, we look at baseline results from a cluster preference randomised control trial with consultants either “using” or “not using” the PCI package in clinic to identify patient...
Wed Jul 01, 2020 03:00
We initially conducted a pilot study to evaluate the impact of botulinum toxin A (BtA) on increased masseteric mass associated with pain. After injection we assessed its impact on the muscle mass and the impact, if any, on reported pain, in a group of 10 patients who were refractory to conservative management. Results of this pilot study indicated that clenched and unclenched muscle dimensions showed no significant reduction (-0.82 clenched and −1mm unclenched). However, what did prove to be significant...
Wed Jul 01, 2020 03:00
While a simple interrupted sutured anastomosis remains the gold standard in microsurgery, the introduction of the microanastomotic coupler device (MACD) has decreased procedure time and thrombosis risk, and improved the patency of venous anastomoses. The aim of this review is to update the evidence-based advantages of the MACD on arteries, based on clinical and experimental data, and to compare them to the hand-sewn approach in free flap transfer. All relevant articles that appeared in the PubMed...
Wed Jul 01, 2020 03:00
In Leeds, nurse-led oral and maxillofacial oncology clinics are a vital part of the care of patients who are undergoing treatment for head and neck cancer.1 Although our service continues to evolve, it has taken a considerable amount of preparation and around six years to develop the credible, efficient, and quality service that exists today. The time it takes to implement a nurse-led clinic should not be underestimated.
Wed Jul 01, 2020 03:00
The lingual nerve is at risk of damage during mandibular third molar (M3M) surgery. Current trends to avoid lingual retraction and prevent injury to the nerve run counter to the surgical principles of locating and protecting important structures. To our knowledge, the last review of this subject only considered repurposed lingual retractors such as the Howarth. Other studies have reported the use of purpose-built retractors with improved outcomes for lingual nerve injuries. This systematic review...
Wed Jul 01, 2020 03:00
We thank Uppal and Shikha for their kind comments about our recent paper which was written with the intention of further raising human factors (HF) awareness in OMFS.1 We have been involved in HF promotion, teaching and training for many years and have published widely in this area. The author(s) highlight the discontinuity between HF initiatives to improve patient safety within individual hospital Trusts and Deaneries and the need for support from National Organisations including the Royal Colleges,...
Wed Jul 01, 2020 03:00
The aim of our study was to compare the biomechanical stability of three different systems used to fix mandibular condylar fractures on synthetic polyurethane mandibles using a servohydraulic testing unit and finite element analysis (FEA). We measured the resistance to displacement loads causing 1.75 and 3.5mm displacements of the fragments, and the maximum resistance values before failure of the fixation system in 30 condylar necks of 15 polyurethane mandible models. The three subgroups investigated...
Wed Jul 01, 2020 03:00
This article discusses the algorithms and published practice patterns on perioperative analgesia for thyroid and parathyroid surgery. This includes medications and techniques used for general anesthesia, local anesthesia including nerve block methods, and oral medication used for postoperative pain control. The authors also discuss multimodality pain control and the increased trend to reduce opioid analgesics without inadequate pain control or patient satisfaction.
Wed Jul 01, 2020 03:00
This article reviews the evidence regarding current perioperative pain management strategies in pediatric patients undergoing otolaryngologic surgery. Pediatric otolaryngology is a broad field with a wide variety of surgical procedures that each requires careful consideration for optimal perioperative pain management. Adequate pain control is vital to ensuring patient safety and achieving successful postoperative care, but many young children are limited in their capacity to communicate their pain...
Wed Jul 01, 2020 03:00
Presentation of Case. Dr. Aditya Bardia: A 62-year-old woman was evaluated at this hospital after she had identified a mass in her left breast, confirmed by her physician on physical examination, during the pandemic of coronavirus disease 2019 (Covid-19), the disease caused by severe acute…
Wed Jul 01, 2020 03:00
Type 2 Diabetes Mellitus (T2DM) is well known to include an inflammatory component that has been considered to be related to diabetic complications. Diabetic nephropathy (DN) is one of the significant complications as it constitutes the most frequent cause of end-stage renal disease. Tumor Necrosis Factor-α (TNF-α) is known as a multifunctional proinflammatory cytokine which is associated with some pathological processes such as immunoregulation, proliferation, inflammation, and apoptosis. The aim...
Wed Jul 01, 2020 14:35
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