J Neurol Surg B Skull BaseDOI: 10.1055/s-0040-1713771 Objectives Postoperative meningitis is a rare but potentially fatal complication of endoscopic endonasal skull base surgery. Prophylactic antibiotic use varies considerably worldwide. We sought to analyze the safety of a single-agent, single-dose protocol. Design, Setting, and Participants A retrospective review of 422 procedures performed during 404 admission episodes from 2009 to 2019, encompassing sella, parasella, and...
Wed Jul 01, 2020 02:00
J Neurol Surg B Skull BaseDOI: 10.1055/s-0040-1713103 Background Facial nerve palsy is one of the most frequent complications after resection of vestibular schwannomas (VS). Several mechanisms have been implicated in the poor postoperative facial nerve outcome. Adherence between the facial nerve and tumor capsule is one of the most relevant factors. There is no clear preoperative parameter permitting identification of these adhesions. Objective The aim of this study was to...
Wed Jul 01, 2020 02:00
J Neurol Surg B Skull BaseDOI: 10.1055/s-0040-1701237Aneurysms of the posterior circulation pose a unique challenge due to higher rupture rates, higher recurrence rates following endovascular treatment, and extended open cranial base approaches required to reach the ventrally located brainstem circulation. While endovascular therapy has made tremendous strides in successful treatment for most posterior circulation aneurysms, open microscopic approaches remain essential in specific circumstances....
Wed Jul 01, 2020 02:00
Background and Objectives Complete neurosurgical resection of intracranial meningiomas is essential to avoid residual tumor tissue and thus minimize the risk of tumor recurrence. However, local recurrence of meningiomas is not uncommon mainly due to insufficient intraoperative detection of residual tumor tissue within the tumor bulk or peritumoral tissue such as bone and satellite lesions. Although 5‐aminolevulinic acid (5‐ALA) induced fluorescence was found to visualize the majority of meningiomas,...
Wed Jul 01, 2020 13:55
Abstract Background The usefulness of apparent diffusion coefficient (ADC) and diffusion‐weighted magnetic resonance imaging (DWI) in the detection of malignant tumors has been reported. The purpose of this study is to clarify the role of ADC and DWI for diagnosis of skull base tumors. Methods A total of 27 patients with head and neck tumors with skull base invasions undergoing skull base surgery were enrolled in this study. Pathological findings of dural invasion and bone invasion were...
Wed Jul 01, 2020 13:18
The cover image is based on the Original Article Soft Tissue Expander for Vertically Atrophied Alveolar Ridges: Prospective, Multicenter, Randomized Controlled Trial by Jin‐Woo Kim et al., https://doi.org/10.1111/clr.13595.
Wed Jul 01, 2020 13:46
New Findings What is the central question of this review? Is exposure to a hot environment detrimental to neuromuscular performance? What is the main finding and what is its importance? Elevating body temperature improves peak power during short‐duration high‐intensity exercise but trades‐off with an accelerated rate of decay. Higher muscle temperatures and crossbridge cycling rate resemble a shift in contractile characteristic to a faster phenotype. Prolonged moderate‐intensity...
Wed Jul 01, 2020 22:34
New Findings What is the topic of this review? The aim is to examine the influence of hypoxia on thermoregulatory and cardiovascular control in the cold. What advances does it highlight? Exposure to hypoxia seems to alter both thermoregulatory and cardiovascular control, but these conclusions are based on limited data and this review highlights the need for future research in this area. Abstract Cold stress and hypoxia have been the subject of research for decades; however,...
Tue Jun 30, 2020 15:21
New Findings What is the central question of this study? Does available comparative data provide empirical evidence that humans are adapted to endurance running at high ambient temperatures? What is the main finding and its importance? Comparing the results of races that pit man against horse, we find that ambient temperature on race day has less deleterious effects on running speed in humans than it does on their quadrupedal adversary. This is evidence that humans are adapted for endurance...
Tue Jun 30, 2020 15:20
Objectives/Hypothesis To identify medical risk factors associated with auditory neuropathy spectrum disorder (ANSD). Study Design Retrospective case–control study. Methods During a 2‐year period (2013–2014) patients with newly diagnosed ANSD were identified at a tertiary care facility. Twenty‐two patients (n = 22) were identified aged 0.5 to 8.1 years. There were 15 males and seven females. Sixteen had bilateral, four had left‐sided, and two had right‐sided ANSD. Two age‐matched, side‐matched,...
Wed Jul 01, 2020 21:24
Objectives Patients with chronic rhinosinusitis (CRS) often describe alterations in sense of taste. These complaints have historically been attributed to olfactory dysfunction; however, there is evidence of direct, objective, gustatory disturbances in the setting of CRS that are not thoroughly characterized. This study sought to investigate and summarize gustatory dysfunction experienced by patients with CRS. Methods PubMed, EMBASE, Cochrane Library, Web of Science, and Scopus databases were...
Wed Jul 01, 2020 21:20
Objectives Head and neck cancers (HNC) are associated with significant morbidity. Quality‐of‐life (QoL) analyses can assist with understanding subjective factors shaping the patient experience. Here, we assess for patient and/or tumor factors associated with increased pain reporting at the time of initial radiation oncology consultation at a single institution in 2015. Study Design Prospective cross‐sectional questionnaire research. Methods All new patient consultations in 2015 were...
Wed Jul 01, 2020 21:09
Objectives/Hypothesis Antimalarial drugs (chloroquine and hydroxychloroquine) are widely used for the treatment of systemic lupus erythematosus (SLE). However, these drugs may have side effects such as hearing loss. This study aimed to describe the hearing function in SLE patients using antimalarials. Secondarily, this study aimed to investigate whether SLE causes hearing loss and if there are any serological or clinical aspects of this diseases associated with inner ear damage. Study Design...
Tue Jun 30, 2020 22:05
Tue Jun 30, 2020 22:04
Objectives/Hypothesis Our primary objective was to compare differences in survival of patients with high‐grade salivary gland carcinomas (SGCs) receiving adjuvant neutron versus photon radiotherapy using a hospital‐based national cohort and restricted mean survival time (RMST) analysis. Our secondary objective was to compare survival of similar patients treated with primary neutron versus photon radiation. Study Design Multicenter, retrospective population‐based study of patients within the...
Tue Jun 30, 2020 21:23
The Proximal Airway Is a Reservoir for Adaptive Immunologic Memory in Idiopathic Subglottic Stenosis
Objectives/Hypothesis Characterization of the localized adaptive immune response in the airway scar of patients with idiopathic subglottic stenosis (iSGS). Study Design Basic Science. Methods Utilizing 36 patients with subglottic stenosis (25 idiopathic subglottic stenosis [iSGS], 10 iatrogenic post‐intubation stenosis [iLTS], and one granulomatosis with polyangiitis [GPA]) we applied immunohistochemical and immunologic techniques coupled with RNA sequencing. Results iSGS, iLTS,...
Tue Jun 30, 2020 21:19
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