Algorithm for diagnosing defecatory disorders in the upright position. Abstract Background We compared the utility of existing and modified versions of high‐resolution manometry for diagnosing defecatory disorders (DD). Methods In 64 healthy and 136 constipated women, we compared left lateral (LL) and seated manometry, and analyzed with existing (ManoView™) and new methods, for discriminating between constipated patients with normal and prolonged rectal balloon expulsion time...
Wed Jul 01, 2020 18:42
Related Articles Isolated Primary Rhinosporidiosis of the Parotid Duct: A Rare Presentation. Iran J Otorhinolaryngol. 2020 May;32(110):193-196 Authors: Samal S, Pradhan P, Preetam C Abstract Introduction: The primary involvement of the parotid duct in rhinosporidiosis is very rare in clinical practice. Here, we present a case of rhinosporidiosis primarily involving the parotid duct, which was successfully excised through transparotid and transoral...
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Related Articles Paraglottic and Pre-epiglottic Space Abscess in Adults: Report of Two Cases. Iran J Otorhinolaryngol. 2020 May;32(110):187-191 Authors: Sideris G, Sapountzi M, Maragoudakis P, Delides A Abstract Introduction: Acute epiglottitis or supraglottitis is a rapidly progressing upper respiratory tract infection that can often threaten the airway patency. Epiglottic abscess that expands to the paraglottic (PGS) or preepiglottic (PES)...
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Related Articles Inverted Supernumerary Intranasal Teeth as Unusual Indications of Endoscopic Surgery. Iran J Otorhinolaryngol. 2020 May;32(110):181-186 Authors: Accorona R, Colombo G, Ferrari M, Fazio E, Bolzoni-Villaret A Abstract Introduction: Supernumerary teeth are frequently reported in dental clinical practice; however, eruption in nasal cavities and paranasal sinuses is an extremely rare clinical entity. Case Report: We report...
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Related Articles Metachronous Bilateral Silent Sinus Syndrome: A Case Report. Iran J Otorhinolaryngol. 2020 May;32(110):175-179 Authors: Farneti P, Bellusci A, Parmeggiani A, Pasquini E Abstract Introduction: Bilateral silent sinus syndrome (SSS) is a very rare pathology reported only in few papers in literature. Most of the described cases are simultaneous, and only one had a metachronous presentation. The evolutionary phases of the disease...
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Related Articles Variations of Ethmoid Roof in the Iranian Population- A Cross Sectional Study. Iran J Otorhinolaryngol. 2020 May;32(110):169-173 Authors: Moradi M, Dalili B Abstract Introduction: This study aimed to investigate the distribution of ethmoid roof variation and symmetry according to Keros classification. Materials and Methods: This cross-sectional study assessed the paranasal CT scans of 600 patients over 18 years of...
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Related Articles Impact of the Angles of the Septal Deviation on the Degree of the Mastoid Pneumatization. Iran J Otorhinolaryngol. 2020 May;32(110):163-168 Authors: Çelik M, Yegin Y, Olgun B, Altıntaş A, Kayhan FT Abstract Introduction: The aim was to explore the developmental relationships between the angles of septal deviations and the degree of the mastoid pneumatization. Materials and Methods: In total, 143 patients with a diagnosis...
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Related Articles A Dose-Effect Study of Cisplatin Ototoxicity in Albino Guinea Pigs. Iran J Otorhinolaryngol. 2020 May;32(110):155-161 Authors: Salehi N, Akbari M, Pourbakht A, Haghani H, Janahmadi M Abstract Introduction: Cisplatin is one of the most commonly used antineoplastic drugs; nonetheless, its ototoxic dose-limiting side effects have remained a significant challenge in clinical practice. The recognition of the exact template of hearing...
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Related Articles Effects of Rheumatoid Arthritis on the Larynx. Iran J Otorhinolaryngol. 2020 May;32(110):147-153 Authors: Dehghan M, Ahmadi A, Yousefghahari B, Kiakojouri K, Gholinia H Abstract Introduction: The aim of the present study was to compare the videolaryngostroboscopic findings between patients with rheumatoid arthritis and vocally healthy controls. Materials and Methods: This case-control descriptive study was performed...
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Related Articles Investigation of the Paediatric Tracheostomy Decannulation: Factors Affecting Outcome. Iran J Otorhinolaryngol. 2020 May;32(110):139-145 Authors: Chauhan N, Mohindra S, Patro SK, Mathew PJ, Mathew J Abstract Introduction: Evidence for factors determining paediatric tracheostomy decannulation vary extensively; therefore, this prospective observational study aimed to investigate these factors. Materials and Methods:...
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Related Articles Results of End-To-Side Hypoglossal-Facial Nerve Anastomosis in Facial Paralysis after Skull Base Surgery. Iran J Otorhinolaryngol. 2020 May;32(110):133-138 Authors: Dabiri S, Khorsandi Ashtiani M, Moharreri M, Mahvi Khomami Z, Kouhi A, Yazdani N, Borghei P, Aghazadeh K Abstract Introduction: The primary aim of facial reanimation surgery is to restore tone, symmetry, and movement to the paralyzed face. Hypoglossal-facial end-to-side...
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Type 2 Diabetes Mellitus (T2DM) is well known to include an inflammatory component that has been considered to be related to diabetic complications. Diabetic nephropathy (DN) is one of the significant complications as it constitutes the most frequent cause of end-stage renal disease. Tumor Necrosis Factor-α (TNF-α) is known as a multifunctional proinflammatory cytokine which is associated with some pathological processes such as immunoregulation, proliferation, inflammation, and apoptosis. The aim...
Wed Jul 01, 2020 14:35
Objective. In recent years, the role of the modern inflammatory markers TREM-1 (triggering receptors expressed on myeloid cells) and HMGB1 (high mobility group box 1 protein) in tumorigenesis has begun to be studied. Their role in gliomas is not clear. The aim of our study was to find the role of inflammation in gliomas. Patients and Methods. In 63 adult patients with gliomas and 31 healthy controls, the expressions of TREM-1 and TREM-2 on CD14+ blood cells (method: flow cytometry) and the levels...
Wed Jul 01, 2020 14:35
Mucosal Immunology, Published online: 01 July 2020; doi:10.1038/s41385-020-0317-3Brg1 restrains the pro-inflammatory properties of ILC3s and modulates intestinal immunity
Wed Jul 01, 2020 03:00
Wed Jul 01, 2020 03:00
Abstract The meta-analysis and systematic review aimed to evaluate the effect of low-level laser therapy (LLLT) as an adjunct to periodontal surgery in the management of postoperative pain and wound healing. An electronic search in 4 databases (PubMed, Embase, Cochrane, and OpenGrey) was conducted for randomized clinical trials reporting the effectiveness of LLLT used as an adjunct to periodontal surgery to alleviate pain and accelerate wound healing compared with surgery alone....
Wed Jul 01, 2020 03:00
Νέα στοιχεία για τη δυνατότητα του νέου κορωνοϊού SARS-CoV-2 να μολύνει απευθείας τα κύτταρα του καρδιακού μυ αλλά και τον εγκέφαλο, έρχονται στο φως της δημοσιότητας από δύο ξεχωριστές μελέτες. Στην πρώτη μελέτη, σε σχετικό άρθρο που δημοσιεύεται στο Cell Reports Medicine ομάδα ειδικών από το Ινστιτούτο Αναγεννητικής Ιατρικής του Συστήματος Υγείας «Κέδροι του Σινά» στις ΗΠΑ, υποστηρίζει ότι ο ιός έχει την ικανότητα να μολύνει απευθείας τα καρδιακά κύτταρα των ασθενών με λοίμωξη COVID-19. Αν και...
Wed Jul 01, 2020 12:47
Ο υποθυρεοειδισμός στην τρίτη ηλικία (η υπολειτουργία του θυρεοειδούς αδένα έργο του οποίου είναι η παραγωγή ορμονών)-, αποτελεί σύνθετο πρόβλημα ως προς τη διάγνωσή του: τα συμπτώματα στους ηλικιωμένους ασθενείς εκτείνονται σε ένα φάσμα που περιλαμβάνει τυπικά συμπτώματα ωστόσο περιορισμένα, συμπτώματα συνήθη στις πιο νεαρές ηλικίες είτε συμπτώματα που εκφεύγουν της κλασικής συμπτωματολογίας. Σύμφωνα ωστόσο με τους ερευνητές του Πανεπιστημίου Χαρβαρντ υπάρχουν κάποια συμπτώματα χαρακτηριστικά...
Wed Jul 01, 2020 12:20
Μια θεωρία ευρείας αποδοχής, θέλει τις μητέρες να έχουν εξασθενημένες κάποιες εγκεφαλικές λειτουργίες όπως τη μνήμη και την προσοχή. Ποια είναι ωστόσο η αλήθεια; Το ομιχλώδες τοπίο αποφάσισε να ξεκαθαρίσει ερευνητική ομάδα από το Πανεπιστήμιο Purdue, ζητώντας από 70 άτεκνες γυναίκες και 60 μητέρες που είχαν αποκτήσει το παιδί τους τουλάχιστον έναν χρόνο από τη μελέτη, να αξιολογήσουν μέσα από επτά βαθμίδες, ερωτήματα όπως «ποια η ένταση της υπνηλίας που νιώθεις;» ή «πόσο συγκεντρωμένη είναι η προσοχή...
Wed Jul 01, 2020 08:50
Έρευνα από το Πανεπιστήμιο της Δυτικής Αυστραλίας (UWA) ανέδειξε τη διατροφή και συγκεκριμένα ένα πλούσιο σε αντιοξειδωτικά «κοκτέιλ« σε σημαντικό όπλο απέναντι στη νόσο Αλτσχάιμερ. Σύμφωνα με τα ευρήματα που δημοσιεύτηκαν στο Open Biology, μια δίαιτα πλούσια σε θρεπτικά συστατικά και αντιοξειδωτικά μπορεί να αποτρέψει ή ακόμη και να αντιστρέψει τις επιπτώσεις της νόσου. Μάλιστα, η λήψη ενός σχήματος αντιοξειδωτικών σε σταδιακά αυξανόμενες δόσεις αποδείχτηκε πιο αποτελεσματική...
Wed Jul 01, 2020 08:40
Ένα ζεστό μπάνιο δεν αναζωογονεί μόνο τις αισθήσεις, αποφάνθηκαν οι επιστήμονες. Στις ευεργετικές του ιδιότητες όπως η καταπολέμηση των πόνων των αρθρώσεων και η συμβολή του στον ποιοτικό ύπνο και τη μείωση του άγχους, επιστημονικά δεδομένα έρχονται να προσθέσουν μία ακόμη και πιθανώς πιο σημαντική. Ένα ζεστό μπάνιο καθημερινά, σύμφωνα με τη μελέτη του Χάρβαρντ που δημοσιεύτηκε στο Heart, βελτιώνει την υγεία της καρδιάς μειώνοντας έως και κατά 28% τον καρδιαγγειακό κίνδυνο. Το νέο εύρημα προέκυψε...
Wed Jul 01, 2020 08:25
Παιδιά με μικρή διάμετρο των αρτηριών του αμφιβληστροειδούς είχαν περισσότερες πιθανότητες να αναπτύξουν υψηλή αρτηριακή πίεση, ενώ εκείνα με υψηλά επίπεδα αρτηριακής πίεσης ήταν πιο πιθανό να αναπτύξουν δυσλειτουργία στα μικροαγγεία του αμφιβληστροειδούς κατά τη διάρκεια της πρώιμης παιδικής ηλικίας, σύμφωνα με τα αποτελέσματα μιας έρευνα που δημοσιεύθηκε στο Hypertension, της πρώτης που υποδεικνύει αυτή τη σχέση στα παιδιά. Η υψηλή αρτηριακή πίεση, βασικός παράγοντας κινδύνου για την ανάπτυξη...
Wed Jul 01, 2020 08:20
Νέα μελέτη υποστηρίζει ότι η μέτρια κατανάλωση αλκοόλ, δηλαδή ένα με δύο ποτήρια την ημέρα, μπορεί στην πραγματικότητα να διατηρεί τη μνήμη και την ικανότητα σκέψης τόσο στις γυναίκες όσο και στους άνδρες. Η μελέτη που δημοσιεύθηκε στο JAMA Network Open χρησιμοποίησε δεδομένα από μια άλλη, εν εξελίξει κυβερνητική έρευνα υγείας της Αμερικής, στην οποία περιλαμβάνονταν σχεδόν 20.000 άνθρωποι που παρακολουθήθηκαν για ένα μέσο διάστημα εννέα ετών (1996-2008), κατά την έναρξη της μελέτης είχαν μέση ηλικία...
Wed Jul 01, 2020 08:00
Abstract Purpose Surgical series of pineal region gliomas are rarely available. Whereas it is a general assumption that the extent of surgical resection correlates with survival outcomes of intracranial gliomas; the impact of the microsurgical resection on the long-term outcomes of pineal gliomas has been questioned. We present a surgical series of pineal region gliomas with focus on the survival outcome analysis. ...
Wed Jul 01, 2020 03:00
Publication date: Available online 1 July 2020Source: Clinical TherapeuticsAuthor(s): Rajneet K. Oberoi, Weihan Zhao, Matthew Rosebraugh, Federico Mensa, Haoyu Wang, Wei Liu
Wed Jul 01, 2020 22:01
Publication date: Available online 30 June 2020Source: Clinical TherapeuticsAuthor(s): Patrick Davis, John Gaitanis
Wed Jul 01, 2020 22:01
Publication date: Available online 30 June 2020Source: Clinical TherapeuticsAuthor(s): Mika Maeda, Rieko Tanaka, Masako Aso, Yasutoshi Sakamoto, Ildae Song, Michiru Ochiai, Yoshiro Saito, Keiko Maekawa, Noriaki Arakawa, Yasuo Ohno, Yuji Kumagai
Wed Jul 01, 2020 22:01
Publication date: Available online 30 June 2020Source: Clinical TherapeuticsAuthor(s): Jill L. Maron
Wed Jul 01, 2020 22:01
The third coronavirus outbreak in the past 20 years, the SARS-CoV-2 pandemic has caused unprecedented morbidity, mortality, and economic disruption. Safe, effective, and deployable SARS-CoV-2 vaccines are urgently needed to mitigate the consequences of the pandemic and protect from future…
Wed Jul 01, 2020 03:00
In this randomized controlled trial, patients with nonsevere obstructive sleep apnea (OSA) were treated with continuous positive airway pressure (CPAP) or a twin block mandibular advancement splint (MAS). The primary objective was to compare how CPAP and MAS treatments change the health-related quality of life (HRQoL) and self-reported sleep quality of patients after 12 months of treatment. In total, 104 patients were recruited: 55 were allocated to the CPAP treatment group and 49 to the MAS treatment...
Wed Jul 01, 2020 12:50
Publication date: July 2020Source: Acta Histochemica, Volume 122, Issue 5Author(s):
Wed Jul 01, 2020 21:35
Abstract Swallowing can lead to the development of syncope in people who have difficulty swallowing during food intake. It has shown that even spontaneous saliva swallowing can change heart rate variability (HRV). Recently, it has been suggested that changes in heart rate during swallowing may be caused by respiratory activities. In this study, the hypothesis that swallowing induced HRV are caused from breathing changes during swallowing has been tested. For this purpose, electrocardiogram...
Wed Jul 01, 2020 03:00
Publication date: Available online 30 June 2020Source: Clinical NeurophysiologyAuthor(s): Ganne Chaitanya, Emilia Toth, Diana Pizarro, Auriana Irannejad, Kristen Riley, Sandipan Pati
Wed Jul 01, 2020 21:09
Publication date: Available online 30 June 2020Source: Clinical NeurophysiologyAuthor(s): Christopher Kämpfer, Attila Racz, Carlos M. Quesada, Christian E. Elger, Rainer Surges
Wed Jul 01, 2020 21:09
Abstract Barrett’s esophagus (BE) is an inflammatory condition and a neoplastic precursor to esophageal adenocarcinoma (EAC). Inflammasome signaling, which contributes to acute and chronic inflammation, results in caspase-1 activation leading to the secretion of IL-1β and IL-18, and inflammatory cell death (pyroptosis). This study aimed to characterize caspase-1 expression, and its functional importance, during disease progression to BE and EAC. Three models of disease progression...
Wed Jul 01, 2020 03:00
Abstract Cervical cancer is the most common malignant tumor of the genital tract in females worldwide. Persistent human papillomavirus (HPV) infection is closely associated with the occurrence of cervical cancer. No licensed therapeutic HPV vaccines for cervical cancer are currently available. In our previous study, we demonstrated that the vaccine containing the HPV16 E7 43-77 peptide and the adjuvant unmethylated cytosine-phosphate-guanosine oligodeoxynucleotide elicited significant...
Wed Jul 01, 2020 03:00
Cancer Biotherapy and Radiopharmaceuticals, Ahead of Print.
Mon Jun 29, 2020 10:00
Abstract Posterior pituitary tumors are rare nonneuroendocrine neoplasms originating in the neurohypophysis that lack hormonal secretory capacity. Surprisingly, these tumors are relatively frequently associated with adenohypophyseal syndromes of hormonal hypersecretion such as Cushing’s disease and acromegaly. Fifteen cases of posterior pituitary tumor associated with hypercortisolism have been reported to date, 13 of them were pituicytomas (Pi) and 2 were granular cell tumors...
Wed Jul 01, 2020 03:00
Zusammenfassung Hintergrund Prognostische und prädiktive Biomarker sind für eine personalisierte Therapiesteuerung beim Plattenepithelkarzinom des Kopf- und Halsbereichs (HNSCC) von klinischem Interesse. Fragestellung Die DNA-Methylierung als epigenetischer Mechanismus der Genregulation könnte eine Quelle geeigneter prognostischer und prädiktiver Biomarker...
Wed Jul 01, 2020 03:00
Publication date: Available online 30 June 2020Source: Journal of ProteomicsAuthor(s): Karim Hayoun, Jean-Charles Gaillard, Olivier Pible, Béatrice Alpha-Bazin, Jean Armengaud
Wed Jul 01, 2020 20:30
Publication date: Available online 1 July 2020Source: Clinical ImagingAuthor(s): Chenggong Yan, Jie Lin, Yikai Xu
Wed Jul 01, 2020 20:24
Publication date: Available online 30 June 2020Source: Academic RadiologyAuthor(s): Andrew D. Schweitzer, David Sarkany
Wed Jul 01, 2020 20:20
Publication date: Available online 30 June 2020Source: Academic RadiologyAuthor(s): Andrea Šprláková-Puková, Alena Štouračová, Martin Repko, Eva Koriťáková, Jaroslav Tintěra, Marek Dostál, Tomáš Otaševič
Wed Jul 01, 2020 20:20
Publication date: Available online 30 June 2020Source: Academic RadiologyAuthor(s): Andrew Kanawati, Renan Jose Rodrigues Fernandes, Aaron Gee, Jennifer Urquhart, Fawaz Siddiqi, Kevin Gurr, Chris Bailey, Parham Rasoulinejad
Wed Jul 01, 2020 20:20
Publication date: Available online 30 June 2020Source: Academic RadiologyAuthor(s): Aydan Avdan Aslan, Serap Gültekin, Güldal Esendağli Yilmaz, Osman Kurukahvecioğlu
Wed Jul 01, 2020 20:20
Publication date: Available online 30 June 2020Source: Academic RadiologyAuthor(s): Wendie A. Berg, JoAnn Pushkin
Wed Jul 01, 2020 20:20
This paper aims to present a method to form smooth and well-controlled films of silver chloride (AgCl) with designated coverage on top of thin film silver electrodes.
Wed Jul 01, 2020 20:07
Publication date: Available online 30 June 2020Source: Journal of Cranio-Maxillofacial SurgeryAuthor(s): Mohamed Mounir, Adel Abou-ElFetouh, Waleed ElBeialy, Ragia Mounir
Wed Jul 01, 2020 20:02
ObjectivesTo investigate temporal trends in the ‘healthy soldier effect’ (HSE) among 28 300 Royal Norwegian Navy servicemen who served during 1950–2004.MethodsStandardised mortality ratios (SMRs) for all causes, diseases and external causes were calculated from national rates for the entire study period (1951–2017), and for seven successive follow-up periods after the first recorded day of Naval service, for the overall cohort and for two subgroups: land-based personnel and vessel crews. Poisson...
Wed Jul 01, 2020 19:00
Publication date: Available online 30 June 2020Source: International Journal of Radiation Oncology*Biology*PhysicsAuthor(s): Martin Voss, Marlies Wagner, Nina von Mettenheim, Patrick N. Harter, Katharina J. Wenger, Kea Franz, Jörg Bojunga, Manuela Vetter, Ruediger Gerlach, Michael Glatzel, Frank Paulsen, Elke Hattingen, Oliver Baehr, Michael W. Ronellenfitsch, Emmanouil Fokas, Detlef Imhoff, Joachim P. Steinbach, Claus Rödel, Johannes Rieger
Wed Jul 01, 2020 20:00
Abstract Cisplatin is a chemotherapeutic agent effective against head and neck carcinoma but unfortunately it is cochleotoxic. This study has been designed to investigate the efficacy of OAE in identifying early effects of cisplatin on the cochlea and the importance of protocol for audiological monitoring of cisplatin induced ototoxicity. This is a prospective observational study conducted from October 2012 to September 2014 on 70 patients, receiving Cisplatin for various malignant...
Wed Jul 01, 2020 03:00
Abstract There have been isolated attempts to implement newborn hearing screening at various setups across India. However, none of these attempts has followed a holistic model comprising of multiple components. Therefore, a need was felt to design and implement a comprehensive universal newborn hearing-screening model to, improve follow-up, and provide practically implementable solutions for developing economies. The model was conceptualized after a detailed preliminary planning...
Wed Jul 01, 2020 03:00
Publication date: Available online 1 July 2020Source: Auris Nasus LarynxAuthor(s): Stefan Trabut, Hergen Friedrich, Marco Caversaccio, Simona Negoias
Wed Jul 01, 2020 19:33
Publication date: Available online 1 July 2020Source: Ultrasound in Medicine & BiologyAuthor(s): Judith T. Pruijssen, Chris L. de Korte, Iona Voss, Hendrik H.G. Hansen
Wed Jul 01, 2020 19:24
Publication date: Available online 30 June 2020Source: Ultrasound in Medicine & BiologyAuthor(s): Kush Tripathi, Tongsheng Zhang, Nathan McDannold, Yong-Zhi Zhang, Gösta Ehnholm, Yoshio Okada
Wed Jul 01, 2020 19:24
Publication date: Available online 30 June 2020Source: Behavioural Brain ResearchAuthor(s): Nurul Aqmar Mohamad Nor Hazalin, Ping Liao, Zurina Hassan
Wed Jul 01, 2020 19:24
Allocentric coordinate spatial representations are impaired in aMCI and Alzheimer’s Disease Patients
Publication date: Available online 30 June 2020Source: Behavioural Brain ResearchAuthor(s): Gennaro Ruggiero, Francesco Ruotolo, Alessandro Iavarone, Tina Iachini
Wed Jul 01, 2020 19:24
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