Abstract Purpose To investigate the effects of deep brain stimulation (DBS) electrodes on the brain of a dystonic pediatric patient submitted to bilateral DBS of the globus pallidus internus (GPI). Methods An 8-year-old male patient underwent bilateral DBS of GPI for status dystonicus. He died 2 months later due to multiorgan failure triggered by bacterial...
03:00
Abstract Purpose Tumorigenesis of medulloblastoma is believed to be associated with granule cell progenitor neurogenesis of the cerebellum. Nevertheless, congenital medulloblastomas are rarely found. Here, we report a case of congenital medulloblastoma that showed spontaneous albeit transient regression. Methods A one-month-old baby presented with...
Wed Jul 01, 2020 03:00
Wed Jul 01, 2020 03:00
Abstract Aim Primary thyroid lymphoma (PTL) is a rare malignant disease. Its prognosis depends on early diagnosis. The role of fine‐needle aspiration (FNA), including smear cytology, cell block (CB) techniques, and immunohistochemistry (IHC) sections in the diagnosis of PTL is still unclear. Here we reported 19 cases of PTL and literature review to evaluate the diagnostic accuracy for lymphoma by cytology. Methods Our study retrospectively reviewed 19 patients diagnosed with PTL at the...
Wed Jul 01, 2020 18:30
Abstract This paper presents an automatic lobe-based labeling of airway tree method, which can detect the bifurcation points for reconstructing and labeling the airway tree from a computed tomography image. A deep learning-based network structure is designed to identify the four key bifurcation points. Then, based on the detected bifurcation points, the entire airway tree is reconstructed by a new region-growing method. Finally, with the basic airway tree anatomy and topology knowledge,...
02:57
Summary The 2019 revised NICE guidance (TA566) on cochlear implantation (CI) lowered the audiological threshold at which patients become eligible for CI. NICE estimates this will result in a 70% increase in CI by 2024/25. We performed a retrospective audit of all audiograms performed at East Kent Hospitals University Foundation Trust (serving a population of 695,000 people) over the last 6 years. We identified how many patients were eligible for CI using both the 2009 guidelines and the...
Wed Jul 01, 2020 22:58
Abstract There were 24,719 emergency admissions for epistaxis in English NHS trusts from April 2017‐April 2018.1 Epistaxis is initially managed with external nasal pressure and ice, then cautery, nasal packing, surgery or embolisation, in ascending order. There is growing evidence for Floseal use in anterior and posterior epistaxis. Floseal is a hydrophilic, biodegradable matrix haemosealant. The keyreported benefits of Floseal use include: high patient tolerance compared tonasal packing; good...
Wed Jul 01, 2020 22:18
Abstract The article by Bird et al, is an interesting read and I wish to strongly support their recommendations of a more coherent multidisciplinary approach to dysphagia1. UEMS‐ORL are currently in the early stages of forming either an MJC (Multidisciplinary Joint Committee) in Swallowing Disorders or a Thematic Federation in Dysphagia with European colleagues in other relevant specialties and this publication will certainly assist our endeavours.
Tue Jun 30, 2020 18:03
Abstract Try as we might to make the manuscript selection process as objective as possible, the crapshoot element is unquestionable. Prospective papers are being submitted more frequently than ever, which has broadened the number of reviewers. Medical students and senior faculty alike are being tasked with assessing manuscripts. Different levels of experience, knowledge and variable personal research interests introduce undeniable biases in how papers are ultimately critiqued.
Tue Jun 30, 2020 17:45
Abstract The additive sorbitan monolaurate consists of sorbitol (and its anhydrides) esterified with fatty acids derived from coconut oil. It is currently authorised in the European Union and it is intended to be used as a technological additive (functional group of emulsifiers), in feedingstuffs for all animal species, at a maximum concentration of 85 mg/kg complete feed. In 2019, the EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP ) issued an opinion on the safety...
Tue Jun 30, 2020 22:00
Abstract Following a request from the European Commission, the Panel on Additives and Products or Substances used in Animal Feed (FEEDAP ) was asked to deliver a scientific opinion on vermiculite as a feed additive for pigs, poultry, bovines, sheep, goats, rabbits and horses. Vermiculite, which is a magnesium aluminium iron silicate, is intended for use as a technological additive (functional groups: binders and anticaking agents) in premixtures and feedingstuffs for pigs, poultry, bovines, sheep,...
Tue Jun 30, 2020 22:00
Abstract Following a request from the European Commission, the EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA ) was asked to deliver an opinion on the safety of an extension of use of the novel food ‘plant sterol esters’ when added to vegetable fat spreads and to liquid vegetable fat‐based emulsions for cooking and baking purposes pursuant to Regulation (EU ) 2015/2283. Member States expressed concerns in relation to plant sterol oxidation products (POP ) and consumption by non‐target...
Tue Jun 30, 2020 22:00
Abstract Ascorbyl palmitate (E 304(i)) was re‐evaluated in 2015 by the former EFSA Panel on Food Additives and Nutrient sources added to Food (ANS ). As a follow‐up to this assessment, the Panel on Food Additives and Flavourings (FAF ) was requested to assess the safety of ascorbyl palmitate (E 304(i)) for its uses as food additive in food for infants below 16 weeks of age belonging to food categories 13.1.1 (Infant formulae) and 13.1.5.1 (Dietary foods for infants for special medical purposes...
Tue Jun 30, 2020 22:00
Between 16 February and 15 May 2020, 290highly pathogenic avian influenza (HPAI) A(H5) virus outbreakswere reported in Europe in poultry (n=287), captive birds (n=2) and wild birds (n=1)in Bulgaria, Czechia,Germany,Hungary andPolandand two low pathogenic avian influenza (LPAI) A(H7N1) virus outbreaks were reported in poultry in Italy. 258 of 287 poultry outbreaks detected in Europe were secondary outbreaks, suggesting that in the large majoryty of cases the spread of the virus was not due to wild...
Tue Jun 30, 2020 22:00
Several non‐invasive Raman spectroscopy‐based assays have been reported for rapid and sensitive detection of pathogens. We developed a novel statistical model for the detection of RNA viruses in saliva, based on an unbiased selection of a set of 65 Raman spectral features that mostly attribute to the RNA moieties, with a prediction accuracy of 91.6% (92.5 % sensitivity and 88.8 % specificity). Furthermore, to minimize variability and automate the downstream analysis of the Raman spectra, we developed...
Wed Jul 01, 2020 18:35
Abstract Accurate and timely assessment of the severity of burn is essential for the treatment of burns. Currently, although most first‐degree and third‐degree burns are easily diagnosed through visual inspection or auxiliary diagnostic methods, the second‐degree burn is still difficult to distinguish due to the ambiguity boundaries of second‐degree with first‐degree and third‐degree burns. In this study, we proposed a non‐invasive technique by combing photoacoustic imaging (PAI) and optical coherence...
Wed Jul 01, 2020 18:34
Abstract Objectives To determine the effects of hyaluronic acid (HA) as an adjunct to temporomandibular joint (TMJ) arthroscopy, relative to standard TMJ arthroscopy, in Wilkes stage‐III and ‐IV patients. Methods A randomized clinical trial design was utilized (ClinicalTrials.gov NCT04110587). The 51 patients were allocated to a TMJ arthroscopy (n = 25) or a TMJ arthroscopy plus HA (n = 26) group. Visual analog scale joint pain scores, maximum mouth opening (MMO), and muscle pain were measured...
Wed Jul 01, 2020 20:53
Abstract Objectives To identify factors which influence the intraoral prevalence of human herpes viruses using mucosal swabs, saliva samples and qPCR analysis. Methodology In this cross‐sectional observational study, matched saliva and oral swabs were collected from a total of 115 subjects: 70 immunocompetent subjects with no mucosal abnormalities, 22 with mucosal abnormalities and 23 therapeutically immunocompromised individuals. Extracted DNA was analysed by multiplex qPCR for detection...
Wed Jul 01, 2020 19:52
Abstract The adoption of the global strategy for human resources for health by the WHO in 2016 points to the ever pressing need for sufficient human resources for health (Organization, 2016). The FDI has thus proposed for appropriate planning and distribution of Human resources for oral health to meet the oral health needs of the world’s rapidly growing and aging population (Glick et al., 2012). Oral diseases are a global concern and affect some over 3.5 billion people across the globe (Kassebaum...
Wed Jul 01, 2020 19:44
Abstract Objective In the present study, we aimed to investigate the prognostic value of RUNX1 expression in 76 patients with adenoid cystic carcinoma. Materials and Methods All cases were arranged in tissue microarray blocks and submitted to immunohistochemistry against RUNX1. These results were statistically correlated with clinicopathologic features, including age, gender, tumour site, tumour size, lymph node status, AJCC clinical stage, distant metastasis, treatment, recurrences, follow‐up,...
Wed Jul 01, 2020 17:34
Abstract Objectives This study aimed to investigate the effects of intermittent parathyroid hormone (iPTH) on the stability of orthodontic retention and to explore the possible regulatory role of insulin‐like growth factor‐1 (IGF‐1) in this process. Methods Forty‐eight 6‐week‐old male Wistar rats were adopted in this study. An orthodontic relapsing model was established to investigate the effects of iPTH on orthodontic retention. In vitro, an immortalized mouse cementoblast cell line OCCM‐30...
Tue Jun 30, 2020 16:21
Abstract The outbreak of novel communicable diseases urges epidemiologic and clinical researchers to establish highly sensitive case definitions to track all true positive cases; therefore, there is emerging evidence on the oral lesions that may be indicative of the coronavirus disease (COVID‐19)
Tue Jun 30, 2020 11:44
Sparkling or plain, water gives you life. (ExplorerBob/Pixabay/)The recommended water intake for any adult lands at around 64 ounces, but we often forget to do even half of that. Many doctors note that having a reliable water bottle with you will help you remember to stay hydrated. These water bottles are insulated to keep your water cold on a hot day, but also for easy consumption at your desk or on the road. It’s also a great way to reduce plastic waste. Stay hydrated with our favorite water bottles...
02:31
Keep your refreshments refreshing wherever you go. (Cinthia Escalante via Unsplash/)Having a sturdy, reliable freezer bag during a road trip or on your next grocery run can save you from a messy situation. Who wants melted ice cream all over the car seat? Whether you’re a regular camper or just doing a quick meal delivery, it pays to have compartments to keep everything fresh and cold. These insulated freezer bags are lightweight, come with said handy compartments, and can stand up to the elements.Check...
02:13
Focus on more than personal growth. (Markus Spiske via Unsplash/)It’s never too late to learn to grow your own produce, and raised vegetable beds are one of the easiest and most space effective ways to get started. They’re excellent for small yards, patios, or in situations where growing space is ample, but you don’t want to alter the environment by planting directly into the earth. There are two main types: vegetable beds with raised walls that you set directly onto the ground, or planter boxes...
01:16
Beavers are moving onto the icy tundra (Pixabay/)Carbon pollution is causing all sorts of weird effects on the planet, including dramatic weather shifts and reshuffling ecosystems. Every day brings a new surprise driven by the cascading impacts of warming the Earth. Now, a new study in Environmental Research Letters shows that a warming climate may have unleashed beavers upon the tundra in the Alaskan Arctic—and their activities could be accelerating the loss of permafrost.In Alaska and Canada, beavers...
01:00
SpaceShipTwo was released from the mothership at 51,000 feet. ( Courtesy Virgin Galactic/)This story originally featured on Flying Magazine.Virgin Galactic’s SpaceShipTwo last week completed its second successful test flight from Spaceport America in Truth or Consequences, New Mexico, marking another important milestone toward the launch of Virgin Galactic’s commercial service. The company said in a news release that Mark “Forger” Stucky and Michael “Sooch” Masucci, both commercial astronauts, commanded...
Wed Jul 01, 2020 23:08
For projects of all sizes. (Volha Flaxeco via Unsplash/)Sewing machines can look intimidating with tons of stitch types and features, not to mention the buttons and pedals. But just because you’ve never operated a sewing machine before—or perhaps never hand sewn, either—doesn’t mean it has to be a major challenge. Here are our favorite beginner-friendly models, perfect for someone who has never heard of a bobbin or tried to glue a patch into the knee of their jeans.The amateur-hour choice you’ll...
Wed Jul 01, 2020 22:46
Is this image wiggling, or is it just me? (PopSci/)We know you are bored at home right now—we are too. Here are some puzzles and brainteasers to challenge your family and friends with, either in person or over video chat.Look at the patterned image above. With the screen fixed, the design remains still. But scroll or physically move your screen ever so slightly, and the decorative display picks up speed.What’s driving this delusive dynamism, says neuroscientist Stephen Macknik at SUNY Downstate Medical...
Wed Jul 01, 2020 21:00
Game on! (Dave Photoz via Unsplash/)A board game is a great way to bring the family together—or to bring out a competitive spirit—but there are only so many times you can play the same classics before they start feeling a little old. Here are some excellent titles for families looking to branch out, whether in storytelling or challenge level.Trade resources and build cities. (Amazon/)Settlers of Catan is the most well-known, family-friendly choice for players looking to dip a toe into the world of...
Wed Jul 01, 2020 20:53
If you get lost in the wilderness, finding shelter should be one of your top priorities. (USFWS/)This story was originally featured on Outdoor Life.A survival shelter can be something you build, with tools or your bare hands. It can also be something you find, ready-to-use and provided by nature. Since exposure is one of the top threats in a wilderness survival setting, learning how to find shelter quickly can save your life. The landscape can provide many different kinds of shelters if you just...
Wed Jul 01, 2020 19:07
Facebook will always be "free." (Stan Horaczek /)More than 300 advertisers have recently jumped ship—at least temporarily—from Facebook’s advertising platform in response to the company’s handling of hate speech. Massive companies such as Coca-Cola and Unilever—previously some of the biggest ad buyers on the platform—joined a growing group of companies that pulled their ad dollars from the social network around the NAACP’s #StopHateforProfit boycott. It comes at a time when marketing budgets have...
Wed Jul 01, 2020 18:40
Eco-friendly and disposable options. (Tyler Nix vua/)Making a cup of coffee isn’t just a great way to start the day ... it’s also an art form. There are loads of ways to do it—french press, aeropress, moka pot, pour over—depending on the gear you have, the flavors you prefer, and your favorite preparation methods. If pour over is your go-to, you’ll need to invest in great coffee filters that are reliable, easy to use, and don’t add a paper-y flavor to the mix.We’ve pulled out some of our favorites.Found...
Wed Jul 01, 2020 17:54
Causes of death can be harder to figure out than you'd think. (Image by skeeze from Pixabay /)When someone dies, at first it might seem like there was an obvious reason. But things are rarely that simple, especially when you get the opinion of multiple people—even if those people are experts.Autopsies are one of the ways that pathologists in hospitals and government agencies can investigate someone’s cause of death. But for those of us who aren’t professionally trained, sometimes the wording of the...
Wed Jul 01, 2020 20:25
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